TXNL1 and SH3BP4

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		TXNL1	SH3BP4
Description		thioredoxin like 1	SH3 domain binding protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Cell Nucleus Cytoplasm Cytosol	Nucleus Cytoplasm Clathrin-coated Pit Clathrin-coated Vesicle Extracellular Exosome
	Molecular Function	Disulfide Oxidoreductase Activity	GDP-dissociation Inhibitor Activity Protein Binding Ras GTPase Binding Identical Protein Binding
	Biological Process	Cell Redox Homeostasis Oxidation-reduction Process	Endocytosis Negative Regulation Of Cell Proliferation Positive Regulation Of Autophagy Negative Regulation Of Cell Growth Negative Regulation Of TOR Signaling Negative Regulation Of GTPase Activity Amino Acid Import Regulation Of Catalytic Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways			Amino acids regulate mTORC1
Drugs
Diseases
GWAS		Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Chronotype ( 30696823) Diverticular disease ( 30177863) General risk tolerance (MTAG) ( 30643258) Morning person ( 30696823) Number of sexual partners ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)	Depression in smokers ( 30219690) Dialysis-related mortality ( 21546767) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Obstetric antiphospholipid syndrome ( 28424481) Orofacial clefts ( 22419666)
Interacting Genes		4 interacting genes: HSPB1 PSMC3 SH3BP4 SUMO4	22 interacting genes: C2orf73 CCT3 CEP78 CIZ1 DNAJA4 FKBP4 GAPDHS GIPC1 GKAP1 HSPA5 MPHOSPH8 MRGBP NFU1 PLEKHA1 PRR14 PSMA1 TCP1 TTC1 TXNL1 YWHAE YWHAG ZBTB37
Entrez ID		9352	23677
HPRD ID		04335	09285
Ensembl ID		ENSG00000091164	ENSG00000130147
Uniprot IDs		O43396 V9HW51	Q9P0V3
PDB IDs		1GH2 1WWY
Enriched GO Terms of Interacting Partners?
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