SDR42E1 and HSBP1

		SDR42E1	HSBP1
Description		short chain dehydrogenase/reductase family 42E, member 1	heat shock factor binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton
	Molecular Function	3-beta-hydroxy-delta5-steroid Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor	Transcription Corepressor Activity Protein Binding Identical Protein Binding
	Biological Process	Steroid Biosynthetic Process Oxidation-reduction Process	Negative Regulation Of Transcription By RNA Polymerase II Muscle Contraction Endodermal Cell Differentiation Cellular Heat Acclimation Regulation Of Cellular Response To Heat
Pathways			HSF1 activation Attenuation phase HSF1-dependent transactivation
Drugs
Diseases
GWAS			Lead levels ( 26025379) Metabolite levels ( 23823483) Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		2 interacting genes: HSBP1 SRPK2	15 interacting genes: CCHCR1 CD1B HSF1 HSPA1A KIAA1217 KIFC3 KRTAP10-3 KRTAP10-7 LNX1 MPHOSPH6 NOTCH2NLA RPL13 SDCBP SDR42E1 WASHC3
Entrez ID		93517	3281
HPRD ID		17118	05185
Ensembl ID		ENSG00000184860	ENSG00000230989
Uniprot IDs		Q8WUS8	O75506
PDB IDs			3CI9
Enriched GO Terms of Interacting Partners?
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