HAUS8 and HAUS6

Number of citations of the paper that reports this interaction (PubMedID 19369198)
87

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HAUS8	HAUS6
Description		HAUS augmin like complex subunit 8	HAUS augmin like complex subunit 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Cytoplasm Centrosome Cytosol Nuclear Microtubule HAUS Complex	Centrosome Spindle Cytosol Microtubule Nuclear Speck Centriolar Satellite HAUS Complex
	Molecular Function	Molecular_function Protein Binding Microtubule Binding	Molecular_function Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking	G2/M Transition Of Mitotic Cell Cycle Centrosome Cycle Regulation Of G2/M Transition Of Mitotic Cell Cycle Spindle Assembly Cell Division Ciliary Basal Body-plasma Membrane Docking
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs
Diseases
GWAS		Mosquito bite size ( 28199695) Selective IgA deficiency ( 27723758)	Prostate cancer ( 29892016) Prostate cancer (early onset) ( 29892016) Pulse pressure ( 30224653 30578418) Type 2 diabetes ( 30297969)
Interacting Genes		4 interacting genes: APP HAUS5 HAUS6 HSPB1	3 interacting genes: APP HAUS8 KDM1A
Entrez ID		93323	54801
HPRD ID		11318	13302
Ensembl ID		ENSG00000131351	ENSG00000147874
Uniprot IDs		Q9BT25	Q7Z4H7
PDB IDs
Enriched GO Terms of Interacting Partners?
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