CD163 and ERC1

		CD163	ERC1
Description		CD163 molecule	ELKS/RAB6-interacting/CAST family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Endocytic Vesicle Membrane	Golgi Membrane Cytoplasm Centrosome IkappaB Kinase Complex Cell Junction Ciliary Basal Body Presynaptic Membrane Synapse
	Molecular Function	Scavenger Receptor Activity Protein Binding	Protein Binding Rab GTPase Binding PDZ Domain Binding Leucine Zipper Domain Binding Cadherin Binding
	Biological Process	Receptor-mediated Endocytosis Acute-phase Response	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Multicellular Organism Development Protein Transport Retrograde Transport, Endosome To Golgi Negative Regulation Of Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways		Scavenging of heme from plasma CD163 mediating an anti-inflammatory response
Drugs		WF10
Diseases
GWAS		Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899) Hematological and biochemical traits ( 20139978) High density lipoprotein cholesterol levels ( 29083408)	Body mass index ( 26426971) Forehead morphology ( 29921221) Height ( 29782485) Lumbar spine bone mineral density ( 22504420)
Interacting Genes		5 interacting genes: CSNK2B ERC1 HP MYH9 PRKCA	19 interacting genes: APP CD163 CRIP1 DNAJC5 FGF23 FPR2 GALNT8 GPRC5D IFFO1 ITSN2 MRTFB NCAPD2 PPFIA1 PRMT8 RAB6A RAB6B RIMS1 SRPK2 YWHAG
Entrez ID		9332	23085
HPRD ID		05708	06181
Ensembl ID		ENSG00000177575	ENSG00000082805
Uniprot IDs		Q86VB7	G8JLD3 Q8IUD2 X6RLX0
PDB IDs
Enriched GO Terms of Interacting Partners?
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