CD9 and ITGA3

Number of citations of the paper that reports this interaction (PubMedID 10065872)
10

Data Source:
HPRD (in vitro, in vivo)

		CD9	ITGA3
Description		CD9 molecule	integrin subunit alpha 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle	Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Filopodium Membrane Integrin Alpha3-beta1 Complex Receptor Complex Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Exosome Invadopodium Membrane Cell Periphery Synaptic Membrane Growth Cone Filopodium
	Molecular Function	Integrin Binding Protein Binding	Fibronectin Binding Protease Binding Integrin Binding Protein Binding Collagen Binding Protein Domain Specific Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Platelet Degranulation Cell Adhesion Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Brain Development Negative Regulation Of Cell Proliferation Response To Water Deprivation Oligodendrocyte Development Myoblast Fusion Involved In Skeletal Muscle Regeneration Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Negative Regulation Of Cellular Component Movement Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation Regulation Of Macrophage Migration	Neuron Migration Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heart Development Memory Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Extracellular Matrix Organization Lung Development Regulation Of BMP Signaling Pathway Negative Regulation Of Cell Projection Organization Response To Gonadotropin Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Response To Drug Skin Development Mesodermal Cell Differentiation Leukocyte Migration Maternal Process Involved In Female Pregnancy Nephron Development Dendritic Spine Maintenance Renal Filtration Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin	Basigin interactions Integrin cell surface interactions Integrin cell surface interactions Laminin interactions MET activates PTK2 signaling
Drugs		C31G
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Mean platelet volume ( 22139419 27863252) Paclitaxel-induced neuropathy ( 23776197) Platelet count ( 26805783 22139419)
Interacting Genes		22 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT PRKCA PTGFRN SERPINH1 TSPAN4 VKORC1	15 interacting genes: ADAM9 BIN1 CALR CD151 CD82 CD9 FHL2 FN1 HPS5 HSPD1 ITGB1 LGALS8 RABIF TIMP2 TSPAN4
Entrez ID		928	3675
HPRD ID		00880	05431
Ensembl ID		ENSG00000010278	ENSG00000005884
Uniprot IDs		A6NNI4 B4DK09 P21926	A0A140VJM0 P26006
PDB IDs
Enriched GO Terms of Interacting Partners?
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