CYTH2 and ATP6V0A1

Number of citations of the paper that reports this interaction (PubMedID 21307348)
17

Data Source:
BioGRID (pull down)

		CYTH2	ATP6V0A1
Description		cytohesin 2	ATPase H+ transporting V0 subunit a1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Growth Cone	Vacuolar Proton-transporting V-type ATPase, V0 Domain Cell Lysosomal Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Integral Component Of Membrane Vacuolar Proton-transporting V-type ATPase Complex Nuclear Speck Secretory Granule Membrane Phagocytic Vesicle Membrane Melanosome Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism ATPase Binding
	Biological Process	Endocytosis Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction	Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Neutrophil Degranulation Phagosome Acidification Toxin Transport Proton Transmembrane Transport
Pathways		Intra-Golgi traffic	ROS and RNS production in phagocytes Neutrophil degranulation Insulin receptor recycling Transferrin endocytosis and recycling Ion channel transport
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Formic Acid 1D-myo-inositol 1,4,5-trisphosphate S,S-(2-Hydroxyethyl)Thiocysteine Brefeldin A
Diseases
GWAS		Abstraction and mental flexibility ( 31596458)	Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		31 interacting genes: ADORA2A ALDOA APC ARF1 ARF6 ARFGAP1 ARL4A ARL4D ARRB1 ARRB2 ATP6V0A1 ATP6V0A2 ATP6V0A4 CCDC120 CUX1 CYTIP DOCK1 GGA3 GNAQ INAVA IPCEF1 ITGB2 MAPK6 NUP62 PIK3CA PNPLA2 PRKCA PRKCB PRKCG TCIRG1 TRIM23	5 interacting genes: CLIC1 CYTH2 SEH1L SNX4 ZNF267
Entrez ID		9266	535
HPRD ID		03925	01886
Ensembl ID		ENSG00000105443	ENSG00000033627
Uniprot IDs		Q99418	Q53ET5 Q53X12 Q5CZH6 Q93050
PDB IDs		1PBV 1R8M 1R8Q 1R8S 1S9D 4JMI 4JMO 4JWL 4JXH 4L5M 4Z21
Enriched GO Terms of Interacting Partners?
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