TIMM50 and DNM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
HPRD (two hybrid)

		TIMM50	DNM1
Description		translocase of inner mitochondrial membrane 50	dynamin 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Integral Component Of Membrane Nuclear Speck	Photoreceptor Inner Segment Nucleoplasm Cytoplasm Golgi Apparatus Microtubule Plasma Membrane Synaptic Vesicle Postsynaptic Density Microtubule Cytoskeleton Membrane Membrane Coat Axon Cytoplasmic Vesicle Mitochondrial Membrane Varicosity Dendritic Spine Dendritic Spine Head Synapse Postsynaptic Membrane Extracellular Exosome Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone Membrane Postsynaptic Endocytic Zone Membrane Glutamatergic Synapse
	Molecular Function	RNA Binding Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Tyrosine Phosphatase Activity Interleukin-2 Receptor Binding Protein Binding Ribonucleoprotein Complex Binding	RNA Binding GTPase Activity Protein Binding GTP Binding Microtubule Binding Protein C-terminus Binding SH3 Domain Binding Protein Kinase Binding D2 Dopamine Receptor Binding Identical Protein Binding Protein-containing Complex Binding Nitric-oxide Synthase Binding
	Biological Process	Release Of Cytochrome C From Mitochondria Protein Dephosphorylation Mitochondrial Membrane Organization Protein Import Into Mitochondrial Matrix Peptidyl-tyrosine Dephosphorylation	Mitochondrial Fission G Protein-coupled Receptor Internalization Endocytosis Receptor-mediated Endocytosis Endosome Organization Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Receptor Internalization Ephrin Receptor Signaling Pathway Organelle Fission Regulation Of Synapse Structure Or Activity Modulation Of Chemical Synaptic Transmission Membrane Fusion Postsynaptic Neurotransmitter Receptor Internalization Positive Regulation Of Synaptic Vesicle Endocytosis Toxin Transport Response To Amyloid-beta
Pathways		Mitochondrial protein import	Toll Like Receptor 4 (TLR4) Cascade Retrograde neurotrophin signalling Gap junction degradation Formation of annular gap junctions MHC class II antigen presentation EPH-ephrin mediated repulsion of cells Recycling pathway of L1 Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Attention deficit hyperactivity disorder ( 18839057) Body mass index ( 26426971) Coenzyme Q10 levels ( 27149984)
Interacting Genes		4 interacting genes: DNM1 PAFAH1B2 RAF1 TNFRSF10B	46 interacting genes: AMPH AP2A2 ASB13 BIN1 CABIN1 CAV1 CDK5 CEP126 CLIC3 CLIC4 CLINT1 CTTN DNM2 DNMBP EPS15 FNBP1 GRB2 GRIN1 GRIN2D ITSN1 MAP3K10 MED31 MOB4 NCK1 NCK2 NME2 PACSIN1 PACSIN2 PACSIN3 PFN2 PIAS1 PIK3R1 PIN4 PLCG1 PRKCA PRNP RACK1 SH3GL1 SH3GL2 SH3GL3 SNAP25 SNX9 SRC SUMO1 TIMM50 UBE2I
Entrez ID		92609	1759
HPRD ID		12118	03851
Ensembl ID		ENSG00000105197	ENSG00000106976
Uniprot IDs		A0A024R0M6 Q3ZCQ8	B4DK06 B7ZAC0 Q05193
PDB IDs			1DYN 2DYN 2X2E 2X2F 3SNH 3ZYC 3ZYS 4UUD 4UUK 5D3Q 6DLU 6DLV
Enriched GO Terms of Interacting Partners?
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