RPS6KA5 and DNAJC11

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		RPS6KA5	DNAJC11
Description		ribosomal protein S6 kinase A5	DnaJ heat shock protein family (Hsp40) member C11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Mitochondrial Sorting And Assembly Machinery Complex Mitochondrion MICOS Complex
	Molecular Function	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Negative Regulation Of Cytokine Production Stimulatory C-type Lectin Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Protein Phosphorylation Inflammatory Response Epidermal Growth Factor Receptor Signaling Pathway Axon Guidance Histone Phosphorylation Positive Regulation Of CREB Transcription Factor Activity Positive Regulation Of Histone Phosphorylation Positive Regulation Of Histone Acetylation Intracellular Signal Transduction Histone H3-S10 Phosphorylation Histone H3-S28 Phosphorylation Histone H2A-S1 Phosphorylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of NF-kappaB Transcription Factor Activity Interleukin-1-mediated Signaling Pathway	Cristae Formation
Pathways		ERK/MAPK targets CREB phosphorylation NCAM signaling for neurite out-growth Recycling pathway of L1 CD209 (DC-SIGN) signaling	Cristae formation
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Femoral neck bone mineral density ( 29499414 22504420) Fractures ( 30158200) Heel bone mineral density ( 30598549) Lumbar spine bone mineral density ( 29499414) Multiple sclerosis ( 31604244) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Rosacea symptom severity ( 29771307)
Interacting Genes		59 interacting genes: ACTG1 AKT1S1 ALG8 APP ATF1 ATF2 BAD CEBPB CREB1 CREBBP CRMP1 CSNK2B DDAH2 DNAJC11 EIF4EBP1 EP300 ERH ETV1 EZH2 FN1 GPRASP2 H1-1 H1-5 H2AW H2BC21 H2BC3 H2BU1 H3-4 H3C14 H3C6 H4-16 H4C14 HMGN1 HSPB2 IL17RB ITSN1 MAP3K20 MAPK11 MAPK14 MAPT MBP MDFIC NR4A1 PDLIM1 PLA2G4A RAI1 RELA RNF19A ROBO2 RPA1 SMAD6 SMARCB1 STAT1 STAT3 STK11 TH TXNDC11 UNC119 ZNF775	3 interacting genes: CHD5 LINC00337 RPS6KA5
Entrez ID		9252	55735
HPRD ID		06789	07112
Ensembl ID		ENSG00000100784	ENSG00000007923
Uniprot IDs		O75582	B4DGD5 Q9NVH1
PDB IDs		1VZO 3KN5 3KN6
Enriched GO Terms of Interacting Partners?
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