ATG12 and ATG16L1

Number of citations of the paper that reports this interaction (PubMedID 30778222)
7

Data Source:
BioGRID (biochemical, pull down)

		ATG12	ATG16L1
Description		autophagy related 12	autophagy related 16 like 1
Image
GO Annotations	Cellular Component	Autophagosome Cytosol Phagocytic Vesicle Membrane Phagophore Assembly Site Membrane Atg12-Atg5-Atg16 Complex	Autophagosome Membrane Autophagosome Cytosol Axoneme Phagophore Assembly Site Membrane
	Molecular Function	Protein Binding	Protein Binding Ubiquitin-like Protein Transferase Activity Identical Protein Binding GTPase Binding
	Biological Process	Autophagosome Assembly Autophagy Of Mitochondrion C-terminal Protein Lipidation Viral Process Macroautophagy Autophagy Of Nucleus	Autophagosome Assembly Protein Transport Macroautophagy Negative Stranded Viral RNA Replication
Pathways		Macroautophagy Macroautophagy Pink/Parkin Mediated Mitophagy Receptor Mediated Mitophagy Negative regulators of DDX58/IFIH1 signaling	Macroautophagy Macroautophagy
Drugs
Diseases			Crohn's disease
GWAS			Bilirubin levels ( 31319653) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 28067908 20570966 22936669 22412388 17435756 17554300 21102463 23128233) Inflammatory bowel disease ( 28067908) Pediatric autoimmune diseases ( 26301688)
Interacting Genes		12 interacting genes: APP ATG10 ATG16L1 ATG3 ATG5 ATG7 CRX KRTAP4-12 MDFI PLSCR1 PTK2 SRP19	16 interacting genes: APP ATG12 ATG5 C3 CSNK2A1 CSNK2A2 GAN GIGYF2 NOD1 OPTN PLD3 RAB33A RAB33B SCAP TMEM59 UBC
Entrez ID		9140	55054
HPRD ID		08496	16498
Ensembl ID		ENSG00000145782	ENSG00000085978
Uniprot IDs		O94817	A0A024R494 A0A024R4B6 Q17RG0 Q53SV2 Q676U5
PDB IDs		4GDK 4GDL 4NAW	4GDK 4GDL 4NAW 4TQ0 5D7G 5NPV 5NPW 5NUV 5ZYX
Enriched GO Terms of Interacting Partners?
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