CLDN1 and TJP3

Number of citations of the paper that reports this interaction (PubMedID 10601346)
287

Data Source:
HPRD (in vitro, in vivo)

		CLDN1	TJP3
Description		claudin 1	tight junction protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Bicellular Tight Junction Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lateral Plasma Membrane Protein-containing Complex Tight Junction	Nucleus Nucleoplasm Plasma Membrane Bicellular Tight Junction Cell Junction
	Molecular Function	Virus Receptor Activity Structural Molecule Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Aging Establishment Of Blood-nerve Barrier Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Positive Regulation Of Cell Migration Response To Lipopolysaccharide Cell Junction Maintenance Hyperosmotic Salinity Response Cell-cell Junction Organization Response To Ethanol Viral Entry Into Host Cell Protein Complex Oligomerization Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Establishment Of Skin Barrier Drug Transport Across Blood-nerve Barrier Response To Interleukin-18 Bicellular Tight Junction Assembly Cellular Response To Lead Ion Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Response To Dexamethasone Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Wound Healing Establishment Of Endothelial Intestinal Barrier Liver Regeneration Positive Regulation Of Bicellular Tight Junction Assembly Cellular Response To Butyrate
Pathways		Tight junction interactions
Drugs
Diseases		Neonatal ichthyosis-sclerosing cholangitis (NISCH) syndrome; Ichthyosis, leukocyte vacuoles, alopecia, and sclerosing cholangitis (ILVASC)
GWAS		Optic disc size ( 31809533) Response to antipsychotic treatment in schizophrenia (working memory) ( 21107309)	Cleft lip with or without cleft palate x maternal periconceptional vitamin use interaction (parent of origin effect) ( 31372216)
Interacting Genes		12 interacting genes: BRD4 CLDN3 DRG1 LNX1 MMP14 MMP2 MPDZ PATJ TJP1 TJP2 TJP3 WNK4	5 interacting genes: CLDN1 FASLG GJC1 PATJ TJP1
Entrez ID		9076	27134
HPRD ID		04760	18194
Ensembl ID		ENSG00000163347	ENSG00000105289
Uniprot IDs		A5JSJ9 O95832	O95049
PDB IDs			3KFV
Enriched GO Terms of Interacting Partners?
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