P4HA2 and TNS4

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		P4HA2	TNS4
Description		prolyl 4-hydroxylase subunit alpha 2	tensin 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Intracellular Membrane-bounded Organelle	Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	Procollagen-proline 4-dioxygenase Activity Iron Ion Binding Electron Transfer Activity Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen L-ascorbic Acid Binding	Actin Binding Protein Binding
	Biological Process	Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Electron Transport Chain	Apoptotic Process Protein Localization
Pathways		Collagen biosynthesis and modifying enzymes	MET interacts with TNS proteins
Drugs		Succinic acid L-Proline
Diseases
GWAS		Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Blood protein levels ( 29875488) Crohn's disease ( 28067908 22412388) Giant cell arteritis ( 28041642) Height ( 28552196) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Sum eosinophil basophil counts ( 27863252) Ulcerative colitis ( 28067908)	Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042)
Interacting Genes		7 interacting genes: CLNK CREB3 FHL3 P4HB PRKAR2A PRRC2A TNS4	12 interacting genes: CBL EGFR ERBB3 FKBP10 GSTCD HDAC2 KCTD4 NME4 NR3C1 P4HA2 PIK3R1 RPAIN
Entrez ID		8974	84951
HPRD ID		11862	12223
Ensembl ID		ENSG00000072682	ENSG00000131746
Uniprot IDs		O15460 Q05DA4	Q6PJP3 Q8IZW8
PDB IDs		6EVL 6EVM 6EVN 6EVO 6EVP
Enriched GO Terms of Interacting Partners?
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