CCND3 and CDK14

Number of citations of the paper that reports this interaction (PubMedID 17517622)
21

Data Source:
HPRD (two hybrid, in vivo)

		CCND3	CDK14
Description		cyclin D3	cyclin dependent kinase 14
Image			No pdb structure
GO Annotations	Cellular Component	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Body	Cytoplasmic Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane
	Molecular Function	Protein Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding	Cyclin-dependent Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Cyclin Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Phosphorylation Protein Phosphorylation Signal Transduction T Cell Proliferation Regulation Of Cell Proliferation Mitotic Cell Cycle Phase Transition Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Insulin Receptor Signaling Pathway Cell Division Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle	G2/M Transition Of Mitotic Cell Cycle Protein Phosphorylation Wnt Signaling Pathway Cell Division Regulation Of Cell Cycle Regulation Of Canonical Wnt Signaling Pathway
Pathways		Transcriptional regulation of white adipocyte differentiation MAPK6/MAPK4 signaling Cyclin D associated events in G1 Regulation of RUNX1 Expression and Activity
Drugs
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Crohn's disease ( 28067908) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol ( 30275531) HDL cholesterol levels ( 28334899) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Hematological parameters ( 19820697) High light scatter reticulocyte count ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin ( 29403010 28453575 20139978 27863252 28017375 19862010) Mean corpuscular hemoglobin concentration ( 28017375) Mean corpuscular volume ( 23263863 29403010 28453575 20139978 27863252 28017375 19862010) Metabolite levels (5-HIAA/ MHPG Ratio) ( 23319000) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Neutrophil count ( 21507922) Red blood cell count ( 29403010 20139978 27863252 28017375) Red blood cell traits ( 23222517) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Circulating fibroblast growth factor 23 levels ( 30217807) Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer ( 28429243) Hepatitis B virus-related hepatocellular carcinoma ( 29246937) Pulse pressure ( 30224653 30578418) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		46 interacting genes: AKAP8 APP AREG ATF5 ATP5F1C CASP2 CDK11B CDK14 CDK4 CDK6 CDKN1A CDKN1B CRABP2 DMRTB1 DMTF1 DTNBP1 EFEMP2 EIF3K ETV1 FAS FHL3 GC LSM3 MAF1 MAPK4 MAPK6 MCM10 MYB NCOA2 NME1 NPDC1 PCNA POLD1 POLR3GL PSMC1 QKI RARA RB1 RBL2 RUNX1 SH3GLB2 SIL1 TEX11 TFIP11 TSG101 VDR	13 interacting genes: ACVR1 BMPR1B CCND3 CCNY CDKN1A FBXO7 RB1 SEPTIN8 SMURF1 TGFBR1 YWHAB YWHAE YWHAQ
Entrez ID		896	5218
HPRD ID		00452	15121
Ensembl ID		ENSG00000112576	ENSG00000058091
Uniprot IDs		B3KP19 D6RI00 P30281 Q5T8J1	B4DK59 E7EUK8 O94921
PDB IDs		3G33
Enriched GO Terms of Interacting Partners?
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