SYNGAP1 and MPDZ

  • Number of citations of the paper that reports this interaction (PubMedID 15312654)
  • 97
  • Data Source:
  • HPRD (in vitro, in vivo)

SYNGAP1

MPDZ

Description synaptic Ras GTPase activating protein 1 multiple PDZ domain crumbs cell polarity complex component
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Body mass index ( 26426971)
  • Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143)
  • Late-onset Alzheimer's disease ( 27770636)
  • Schizophrenia ( 30285260)
Interacting Genes 13 interacting genes: CAMK2A DLG3 DLG4 DLGAP4 GRIN1 GRIN2B GRIN2D KDR MPDZ PDGFRB TRIP6 ULK1 ULK2 16 interacting genes: ABCA1 CAMK2A CLDN1 CLDN5 CRHR1 CSPG4 DRD3 F11R HTR2C KIT MTNR1A PLEKHA1 PLEKHA2 RNF5 SYNGAP1 TSC22D2
Entrez ID 8831 8777
HPRD ID 16018 09155
Ensembl ID ENSG00000197283 ENSG00000107186
Uniprot IDs A0A1U9X8L0 B7ZCA0 Q96PV0 O75970
PDB IDs 2FCF 2FNE 2IWN 2IWO 2IWP 2IWQ 2O2T 2OPG 2QG1
Enriched GO Terms of Interacting Partners?
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