SNAP23 and STX1B

Number of citations of the paper that reports this interaction (PubMedID 12651853)
5

Data Source:
BioGRID (pull down)

		SNAP23	STX1B
Description		synaptosome associated protein 23	syntaxin 1B
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Phagocytic Vesicle Membrane SNARE Complex Specific Granule Membrane Specific Granule Azurophil Granule Mast Cell Granule Neuron Projection Extracellular Exosome Tertiary Granule Membrane Presynapse	Nucleus Microtubule Organizing Center Spindle Cytosol Plasma Membrane Endomembrane System Membrane Integral Component Of Membrane Axon SNARE Complex Neuromuscular Junction Presynaptic Active Zone Membrane
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	SNARE Binding Signaling Receptor Binding SNAP Receptor Activity Protein Kinase Binding Protein Domain Specific Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Membrane Fusion	Positive Regulation Of Neurotransmitter Secretion Intracellular Protein Transport Exocytosis Vesicle Docking Involved In Exocytosis Vesicle Fusion Regulation Of Gene Expression Regulation Of Synaptic Vesicle Priming Negative Regulation Of Neuron Projection Development Synaptic Vesicle Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Calcium Ion-regulated Exocytosis Of Neurotransmitter Regulation Of Synaptic Activity Spontaneous Neurotransmitter Secretion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Negative Regulation Of Synaptic Vesicle Recycling Positive Regulation Of Spontaneous Neurotransmitter Secretion Negative Regulation Of Macropinocytosis Positive Regulation Of Excitatory Postsynaptic Potential
Pathways		ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation	Toxicity of botulinum toxin type C (BoNT/C) LGI-ADAM interactions
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756)	Body mass index ( 31453325) Body mass index variance ( 31453325) Dementia with Lewy bodies ( 29263008) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Juvenile myoclonic epilepsy ( 30531953) Parkinson's disease ( 25064009) Psoriasis ( 25574825) Response to metformin (IC50) ( 28173075) Waist circumference ( 31453325) Waist circumference variance ( 31453325)
Interacting Genes		33 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCARB1 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P	6 interacting genes: NPTX1 SNAP23 STXBP1 UNC13B VAMP1 VAMP2
Entrez ID		8773	112755
HPRD ID		03962	18126
Ensembl ID		ENSG00000092531	ENSG00000099365
Uniprot IDs		A0A024R9R8 A8K287 O00161	P61266
PDB IDs		1NHL 3ZUS
Enriched GO Terms of Interacting Partners?
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