MBTPS1 and ZBED8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		MBTPS1	ZBED8
Description		membrane bound transcription factor peptidase, site 1	zinc finger BED-type containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Integral Component Of Membrane	Nucleoplasm
	Molecular Function	Serine-type Endopeptidase Activity	Protein Binding
	Biological Process	Proteolysis Protein Import Into Nucleus Lysosome Organization Cholesterol Metabolic Process Endoplasmic Reticulum Unfolded Protein Response Membrane Protein Intracellular Domain Proteolysis Response To Endoplasmic Reticulum Stress ATF6-mediated Unfolded Protein Response Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Cholesterol Biosynthetic Process Regulation Of Vesicle-mediated Transport
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) ATF6 (ATF6-alpha) activates chaperones Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) CREB3 factors activate genes CREB3 factors activate genes Post-translational protein phosphorylation Assembly of active LPL and LIPC lipase complexes
Drugs
Diseases
GWAS		Iris color (a* coordinate) ( 30895295) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		10 interacting genes: ATF6B BDNF BIRC3 C11orf58 CANX CDK2AP2 SPHK1 TNFRSF14 TNFSF11 ZBED8	8 interacting genes: CEP126 EED EEF1G HSF4 MBTPS1 METTL21A NAB2 SLU7
Entrez ID		8720	63920
HPRD ID		04522	17430
Ensembl ID		ENSG00000140943	ENSG00000221886
Uniprot IDs		Q14703	Q8IZ13
PDB IDs
Enriched GO Terms of Interacting Partners?
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