EIF3I and EIF3B

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		EIF3I	EIF3B
Description		eukaryotic translation initiation factor 3 subunit I	eukaryotic translation initiation factor 3 subunit B
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Synapse Extracellular Exosome Eukaryotic Translation Initiation Factor 3 Complex, EIF3m
	Molecular Function	Translation Initiation Factor Activity Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Translation Initiation Factor Binding Molecular Adaptor Activity
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Regulation Of Translational Initiation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Dimensional psychopathology (Social) ( 29496196)
Interacting Genes		11 interacting genes: EIF3A EIF3B EIF4G1 ESR1 EXOSC6 LIG4 METTL3 PAXIP1 SUMO4 TGFB1 TGFBR2	10 interacting genes: BRCA1 EIF3A EIF3G EIF3I EIF3J EIF4G1 IL2RB PAIP1 RPS6KB1 UPF1
Entrez ID		8668	8662
HPRD ID		04884	06795
Ensembl ID		ENSG00000084623	ENSG00000106263
Uniprot IDs		Q13347 Q5U0F4	A0A024R821 A4D210 P55884
PDB IDs			2KRB 2NLW 5K1H
Enriched GO Terms of Interacting Partners?
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