CBFB and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		CBFB	RAB2A
Description		core-binding factor subunit beta	RAB2A, member RAS oncogene family
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Core-binding Factor Complex	Golgi Membrane Nucleus Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Sequence-specific DNA Binding	GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Protein Polyubiquitination Osteoblast Differentiation Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Lymphocyte Differentiation Myeloid Cell Differentiation Regulation Of Wnt Signaling Pathway Regulation Of Intracellular Estrogen Receptor Signaling Pathway Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Regulation Of Regulatory T Cell Differentiation Regulation Of Keratinocyte Differentiation Regulation Of Myeloid Cell Differentiation Regulation Of Megakaryocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Maturation Regulation Of B Cell Receptor Signaling Pathway Definitive Hemopoiesis Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Bicellular Tight Junction Assembly	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Rab Protein Signal Transduction Post-translational Protein Modification
Pathways		RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Transcriptional regulation by RUNX2 Transcriptional regulation by RUNX2 RUNX1 regulates estrogen receptor mediated transcription Regulation of RUNX1 Expression and Activity RUNX1 regulates expression of components of tight junctions RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function RUNX1 regulates transcription of genes involved in differentiation of HSCs RUNX1 regulates transcription of genes involved in differentiation of HSCs RUNX1 regulates transcription of genes involved in differentiation of keratinocytes RUNX1 regulates transcription of genes involved in differentiation of keratinocytes RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known RUNX1 regulates transcription of genes involved in BCR signaling RUNX1 regulates transcription of genes involved in differentiation of myeloid cells RUNX1 regulates transcription of genes involved in interleukin signaling RUNX1 regulates transcription of genes involved in WNT signaling Regulation of RUNX2 expression and activity Regulation of RUNX2 expression and activity RUNX2 regulates osteoblast differentiation RUNX2 regulates osteoblast differentiation RUNX2 regulates chondrocyte maturation RUNX2 regulates bone development RUNX2 regulates genes involved in cell migration RUNX2 regulates genes involved in cell migration RUNX2 regulates genes involved in differentiation of myeloid cells Regulation of RUNX3 expression and activity RUNX3 Regulates Immune Response and Cell Migration RUNX3 Regulates Immune Response and Cell Migration RUNX3 regulates RUNX1-mediated transcription RUNX3 regulates p14-ARF Estrogen-dependent gene expression Transcriptional regulation of granulopoiesis	Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 27863252)	Estimated glomerular filtration rate ( 31152163) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		9 interacting genes: CBFA2T2 CHGB COPRS CUL5 RAB2A RNF7 RUNX1 RUNX2 RUNX3	19 interacting genes: ASPH BLZF1 CBFB CPA4 FAM114A1 FAM71C GAPDH GDI2 GOLGA2 GORASP2 ICA1 MAPK6 MAPKAPK3 PRKCI RBSN RGS2 RP1 STAMBPL1 TBC1D25
Entrez ID		865	5862
HPRD ID		00418	01539
Ensembl ID		ENSG00000067955	ENSG00000104388
Uniprot IDs		A0A024R6X2 Q13951	A0A024R7V6 P61019
PDB IDs		1CL3 1E50 1H9D 4N9F	1Z0A
Enriched GO Terms of Interacting Partners?
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