Description |
nuclear receptor coactivator 1 |
peroxisome proliferator activated receptor gamma |
Image |
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GO Annotations |
Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
- Genistein
- Corticosterone
- 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3-BENZOXAZOL-5-OL
- 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1-NAPHTHONITRILE
- (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
- [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE
- 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL
- N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE
- 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL
- 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME
- 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-CARBONITRILE
- 2-METHYL-2-(4-{[({4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-5-YL}CARBONYL)AMINO]METHYL}PHENOXY)PROPANOIC ACID
- 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H-INDEN-1-ONE
- 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL
- (1R,3R)-5-[(2E)-3-{(1S,3R)-2,2,3-trimethyl-3-[6,6,6-trifluoro-5-hydroxy-5-(trifluoromethyl)hex-3-yn-1-yl]cyclopentyl}prop-2-en-1-ylidene]cyclohexane-1,3-diol
- (5BETA)-PREGNANE-3,20-DIONE
- Indeglitazar
- (8alpha,10alpha,13alpha,17beta)-17-[(4-hydroxyphenyl)carbonyl]androsta-3,5-diene-3-carboxylic acid
- Myristic acid
- 1,3-CYCLOHEXANEDIOL, 4-METHYLENE-5-[(2E)-[(1S,3AS,7AS)-OCTAHYDRO-1-(5-HYDROXY-5-METHYL-1,3-HEXADIYNYL)-7A-METHYL-4H-INDEN-4-YLIDENE]ETHYLIDENE]-, (1R,3S,5Z)
- Aleglitazar
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- Alpha-Linolenic Acid
- Icosapent
- Troglitazone
- Mesalazine
- Valproic Acid
- Indomethacin
- Rosiglitazone
- Fenoprofen
- Nateglinide
- Sulfasalazine
- Repaglinide
- Telmisartan
- Balsalazide
- Fenofibrate
- Ibuprofen
- Glipizide
- Amiodarone
- Pioglitazone
- Mitiglinide
- Bezafibrate
- Flufenamic Acid
- Resveratrol
- Phthalic Acid
- Capric acid
- Doconexent
- Oleic Acid
- (S)-3-(4-(2-Carbazol-9-Yl-Ethoxy)-Phenyl)-2-Ethoxy-Propionic Acid
- 2-{5-[3-(6-BENZOYL-1-PROPYLNAPHTHALEN-2-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- Reglixane
- Elafibranor
- T131
- CLX-0921
- (2S)-3-(1-{[2-(2-CHLOROPHENYL)-5-METHYL-1,3-OXAZOL-4-YL]METHYL}-1H-INDOL-5-YL)-2-ETHOXYPROPANOIC ACID
- (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid
- 2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID
- (4S,5E,7Z,10Z,13Z,16Z,19Z)-4-hydroxydocosa-5,7,10,13,16,19-hexaenoic acid
- (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid
- (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid
- (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid
- (9S,10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid
- difluoro(5-{2-[(5-octyl-1H-pyrrol-2-yl-kappaN)methylidene]-2H-pyrrol-5-yl-kappaN}pentanoato)boron
- (2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY]PHENYL}PROPANOIC ACID
- 3-(5-methoxy-1H-indol-3-yl)propanoic acid
- Indeglitazar
- (2S)-2-(4-ethylphenoxy)-3-phenylpropanoic acid
- 2-chloro-5-nitro-N-phenylbenzamide
- (2S)-2-(biphenyl-4-yloxy)-3-phenylpropanoic acid
- 3-[5-(2-nitropent-1-en-1-yl)furan-2-yl]benzoic acid
- 2-[(2,4-DICHLOROBENZOYL)AMINO]-5-(PYRIMIDIN-2-YLOXY)BENZOIC ACID
- (5E,14E)-11-oxoprosta-5,9,12,14-tetraen-1-oic acid
- 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE
- Triclosan
- (2S)-2-(4-chlorophenoxy)-3-phenylpropanoic acid
- Aleglitazar
- Clinofibrate
- Lobeglitazone
- Ciglitazone
- Dexibuprofen
- Omega-3 fatty acids
- Curcumin
- Arhalofenate
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Diseases |
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GWAS |
- Asthma ( 29273806)
- Body fat distribution (arm fat ratio) ( 30664634)
- Body fat distribution (trunk fat ratio) ( 30664634)
- Body mass index ( 26426971)
- Body mass index (age <50) ( 26426971)
- Body mass index (age>50) ( 26426971)
- Body mass index x sex x age interaction (4df test) ( 26426971)
- Breast cancer ( 29058716)
- Breast Cancer in BRCA1 mutation carriers ( 29058716)
- Chromium levels ( 26025379)
- Cognitive function ( 28093568)
- Diffuse large B cell lymphoma ( 25261932)
- Hand grip strength ( 29691431)
- Lung adenocarcinoma ( 28604730)
- Lung cancer ( 28604730)
- Lung cancer in ever smokers ( 28604730)
- Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
- Waist circumference adjusted for body mass index ( 28448500)
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- Arterial stiffness index ( 31235810)
- Body mass index ( 28892062 25673413 29273807)
- Cholesterol, total ( 25961943)
- Drug-induced liver injury ( 22968431)
- Endometrial cancer ( 30093612)
- Endometrial cancer (endometrioid histology) ( 30093612)
- Eosinophil counts ( 27863252)
- Eosinophil percentage of granulocytes ( 27863252)
- Eosinophil percentage of white cells ( 27863252)
- Fasting blood insulin ( 25631608)
- Fasting blood insulin (BMI interaction) ( 22581228)
- Fasting blood insulin adjusted for BMI ( 25625282)
- Gut microbiota (functional units) ( 27694959)
- HDL cholesterol ( 30275531)
- Heel bone mineral density ( 30598549)
- Hematocrit ( 27863252)
- Hemoglobin concentration ( 27863252)
- High density lipoprotein cholesterol levels ( 29403010)
- Hip circumference adjusted for BMI ( 25673412)
- Idiopathic osteonecrosis of the femoral head ( 31135556)
- LDL cholesterol ( 25961943)
- LDL cholesterol levels ( 30698716)
- LDL cholesterol levels in current drinkers ( 30698716)
- LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Medication use (drugs used in diabetes) ( 31015401)
- Medication use (HMG CoA reductase inhibitors) ( 31015401)
- Medication use (thyroid preparations) ( 31015401)
- Modified Stumvoll Insulin Sensitivity Index (model adjusted for BMI) ( 27416945)
- Neutrophil percentage of granulocytes ( 27863252)
- Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
- Platelet count ( 29403010)
- Potassium levels ( 29403010)
- Sexual dimorphism in anthropometric traits ( 23754948)
- Systemic lupus erythematosus ( 28714469)
- Type 2 diabetes ( 22885922 18372903 24509480 30054458 29358691 30297969 29632382 31118516 20581827 17463246 30718926 17463248 17463249 28869590)
- Type 2 diabetes (adjusted for BMI) ( 29632382)
- Waist circumference ( 31453325)
- Waist circumference variance ( 31453325)
- Waist-hip ratio ( 25673412)
- Waist-to-hip ratio adjusted for BMI ( 26426971)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
- Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
- Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
- Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
- Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
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Interacting Genes |
81 interacting genes:
AHR
ANKRD11
AR
ARID1A
ARNT
BCL3
CARM1
CCND1
CHMP2A
CIITA
COPS5
CREBBP
CXADR
DDX17
DDX5
EP300
ESR1
ESR2
ESRRA
ESRRG
FOS
FOXA2
FOXO1
GTF2B
HIF1A
HNF1A
HNF4A
HNF4G
JUN
KANK2
KAT2B
MAPK1
NCOR1
NFKB1
NKX2-1
NR1H2
NR1H3
NR1H4
NR1I2
NR1I3
NR2F1
NR2F6
NR3C1
NR3C2
NR4A1
NR5A1
NR5A2
NR6A1
PAGR1
PGR
PPARA
PPARD
PPARG
PPARGC1A
PRMT1
PRMT2
PSMB9
RARA
RARB
RARG
RORA
RORB
RXRA
RXRB
SMARCC1
SMARCE1
SNW1
SRF
STAT3
STAT6
SUMO1
TBP
TEAD1
TEAD2
THRA
THRB
TP53
TRIP4
VDR
YWHAH
YWHAQ
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106 interacting genes:
ALOX15B
ANP32A
APP
BCAS2
BRD8
CDC34
CDK5
CEP350
CNOT1
COPS5
CREBBP
DNTTIP2
EDF1
EGFR
FABP1
FHOD1
FOXO1
GADD45B
GADD45G
GRIP1
HDAC1
HDAC3
HDAC4
HELZ2
HMGA1
IGFBP3
IKBKB
JAZF1
JMJD1C
JUN
JUND
KAT2A
KAT5
KCTD13
KIF11
KIF1A
KLF5
LMO4
LRIF1
MAFF
MAP2K1
MAPK1
MAPK8
MED1
MED24
MFHAS1
MIF4GD
MSX2
MUC1
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NFE2L2
NFE2L3
NFKB1
NFKBIB
NR0B1
NR0B2
NR2E3
NR4A1
NR4A2
NRIP1
NSD1
PAK4
PDIA2
PHB2
PML
POU1F1
PPARGC1A
PPM1B
PRKCA
RAD54L2
RANBP9
RB1
RELA
ROBO4
RXRA
RXRB
RXRG
SERPINH1
SFPQ
SIRT1
SMARCD3
STAT6
STUB1
SVIL
SYT1
TFAP2A
TNP1
TRIM24
TRIP4
UBC
UBE2I
USP7
VDR
ZBTB20
ZBTB3
ZBTB5
ZBTB9
ZNF496
ZNHIT3
ZSCAN1
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Entrez ID |
8648 |
5468 |
HPRD ID |
04070 |
03288 |
Ensembl ID |
ENSG00000084676
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ENSG00000132170
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Uniprot IDs |
Q15788
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A0A494C1F9
D2KUA6
E9PFX5
P37231
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PDB IDs |
1FM6
1FM9
1K4W
1K74
1K7L
1KV6
1N4H
1NQ7
1NRL
1P8D
1PZL
1RDT
1TFC
1U3R
1U3S
1X76
1X78
1X7B
1X7J
1XIU
1XV9
1XVP
1YY4
1YYE
1ZAF
2A3I
2C52
2FVJ
2GTK
2HBH
2HC4
2HCD
2HFP
2NPA
2NV7
2P54
2PRG
3BEJ
3BQD
3CTB
3CWD
3DCT
3DCU
3DR1
3ET1
3ET3
3FEI
3FEJ
3FUR
3FXV
3G8I
3G9E
3GYT
3GYU
3H0A
3HC5
3HC6
3HVL
3IPQ
3IPS
3IPU
3KMR
3LMP
3OKH
3OKI
3OLF
3OLL
3OLS
3OMK
3OMM
3OMO
3OMP
3OMQ
3OOF
3OOK
3P88
3P89
3QT0
3RUT
3RUU
3RVF
3S9S
3T03
3UU7
3UUA
3UUD
3V9Y
3VN2
4DK7
4DK8
4DM6
4DM8
4DQM
4F9M
4FGY
4G1D
4G1Y
4G1Z
4G20
4G21
4G2H
4HEE
4J5X
4JYG
4JYH
4JYI
4MG5
4MG6
4MG7
4MG8
4MG9
4MGA
4MGB
4MGC
4MGD
4RUJ
4RUP
4TUZ
4TV1
4UDA
4UDB
4Y29
5A86
5AVI
5AVL
5AZT
5DSH
5DV3
5DV6
5DV8
5DVC
5DWL
5E7V
5GTN
5GTO
5GTP
5HJS
5JI0
5JMM
5L7E
5L7G
5L7H
5MWP
5MWY
5MX7
5NKY
5NMA
5NMB
5NWM
5OW7
5OW9
5OWD
5Q0J
5Q0K
5Q0L
5Q0M
5Q0N
5Q0O
5Q0P
5Q0Q
5Q0R
5Q0S
5Q0T
5Q0U
5Q0V
5Q0W
5Q0X
5Q0Y
5Q0Z
5Q10
5Q11
5Q12
5Q13
5Q14
5Q15
5Q16
5Q18
5Q19
5Q1A
5Q1B
5Q1C
5Q1D
5Q1E
5Q1F
5Q1G
5Q1H
5Q1I
5X0R
5X8U
5X8W
5Y44
5YCN
5YCP
5YP6
6A5W
6A5X
6A5Y
6A5Z
6A60
6BNS
6E3G
6FO7
6FO8
6FO9
6FOB
6FOD
6GEV
6GG8
6ICJ
6IJR
6IJS
6ILQ
6ITM
6JQ7
6P9F
6SSQ
6U25
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1FM6
1FM9
1I7I
1K74
1KNU
1NYX
1PRG
1RDT
1WM0
1ZEO
1ZGY
2ATH
2F4B
2FVJ
2G0G
2G0H
2GTK
2HFP
2HWQ
2HWR
2I4J
2I4P
2I4Z
2OM9
2P4Y
2POB
2PRG
2Q59
2Q5P
2Q5S
2Q61
2Q6R
2Q6S
2Q8S
2QMV
2VSR
2VST
2VV0
2VV1
2VV2
2VV3
2VV4
2XKW
2YFE
2ZK0
2ZK1
2ZK2
2ZK3
2ZK4
2ZK5
2ZK6
2ZNO
2ZVT
3ADS
3ADT
3ADU
3ADV
3ADW
3ADX
3AN3
3AN4
3B0Q
3B0R
3B1M
3B3K
3BC5
3CDP
3CDS
3CS8
3CWD
3D6D
3DZU
3DZY
3E00
3ET0
3ET3
3FEJ
3FUR
3G9E
3GBK
3H0A
3HO0
3HOD
3IA6
3K8S
3KMG
3LMP
3NOA
3OSI
3OSW
3PBA
3PO9
3PRG
3QT0
3R5N
3R8A
3R8I
3S9S
3SZ1
3T03
3TY0
3U9Q
3V9T
3V9V
3V9Y
3VJH
3VJI
3VN2
3VSO
3VSP
3WJ4
3WJ5
3WMH
3X1H
3X1I
4A4V
4A4W
4CI5
4E4K
4E4Q
4EM9
4EMA
4F9M
4FGY
4HEE
4JAZ
4JL4
4L96
4L98
4O8F
4OJ4
4PRG
4PVU
4PWL
4R06
4R2U
4R6S
4XLD
4XTA
4XUH
4XUM
4Y29
4YT1
5AZV
5DSH
5DV3
5DV6
5DV8
5DVC
5DWL
5F9B
5GTN
5GTO
5GTP
5HZC
5JI0
5LSG
5TTO
5TWO
5U5L
5UGM
5WQX
5WR0
5WR1
5Y2O
5Y2T
5YCN
5YCP
5Z5S
5Z6S
6AD9
6AN1
6AUG
6AVI
6C1I
6C5Q
6C5T
6D3E
6D8X
6D94
6DBH
6DCU
6DGL
6DGO
6DGP
6DGQ
6DGR
6DH9
6DHA
6E5A
6ENQ
6F2L
6FZF
6FZG
6FZJ
6FZP
6FZY
6ICJ
6IJR
6IJS
6ILQ
6IZM
6IZN
6JQ7
6K0T
6MCZ
6MD0
6MD1
6MD2
6MD4
6MS7
6O67
6O68
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Enriched GO Terms of Interacting Partners? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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