USO1 and DUSP12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		USO1	DUSP12
Description		USO1 vesicle transport factor	dual specificity phosphatase 12
Image
GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Nucleic Acid Binding Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Zinc Ion Binding Phosphatase Activity Kinase Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase Mediated Signal Transduction Secretory Granule Localization Transcytosis COPII Vesicle Coating Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus	Cellular Protein Modification Process Protein Dephosphorylation Dephosphorylation Positive Regulation Of Glucokinase Activity Peptidyl-tyrosine Dephosphorylation
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)	Albumin-globulin ratio ( 29403010) Immunoglobulin measurement (zinc sulfate turbidity test) ( 29403010) Non-albumin protein levels ( 29403010)
Interacting Genes		25 interacting genes: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 G3BP2 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A SCFD1 STX5 STXBP1 XPO7 YKT6	12 interacting genes: APP CALCOCO2 CCNH CEP126 EIF5 HSPB8 MBD6 NR1H2 PPP2R3B PTN RABAC1 USO1
Entrez ID		8615	11266
HPRD ID		09135	05323
Ensembl ID		ENSG00000138768	ENSG00000081721
Uniprot IDs		O60763	Q9UNI6
PDB IDs		2W3C	4JNB 4KI9
Enriched GO Terms of Interacting Partners?
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