DOCK7 and GRB7

  • Number of citations of the paper that reports this interaction (PubMedID 21900206)
  • 114
  • Data Source:
  • BioGRID (two hybrid)

DOCK7

GRB7

Description dedicator of cytokinesis 7 growth factor receptor bound protein 7
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Cholesterol, total ( 28270201 19060911 25961943 20686565)
  • Crohn's disease ( 28067908)
  • HDL cholesterol ( 30275531)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol ( 19060911 30275531 25961943 20686565)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535)
  • LDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535)
  • Lipid traits ( 24386095)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Metabolite levels ( 23823483 22916037)
  • Metabolite levels (lipid measures) ( 27005778)
  • Platelet distribution width ( 27863252)
  • Pneumococcal bacteremia ( 27236921)
  • Regular attendance at a gym or sports club ( 29970889)
  • Serum metabolite levels ( 31636271)
  • Serum metabolite levels (CMS) ( 31636271)
  • Total cholesterol levels ( 29403010 30275531)
  • Triglyceride levels ( 31170924 29403010 29615537 30698716)
  • Triglyceride levels in current drinkers ( 30698716)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x long total sleep time interaction (2df test) ( 31719535)
  • Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
  • Triglycerides ( 18193044 20864672 19060911 25961943 20686565)
  • Very long-chain saturated fatty acid levels (fatty acid 20:0) ( 25378659)
Interacting Genes 16 interacting genes: ANXA7 BCL2L1 CDC42 CDKN1A GRB7 NOD2 NSD3 PPP2CB PRNP RAC1 RHOA RPP14 SMN1 SNCA TK1 YWHAG 42 interacting genes: A1BG AGAP1 ATP5F1B CALM1 CAV1 CPNE6 DOCK7 DYNC1I1 EGFR ERBB2 ERBB3 FGB FLAD1 GIGYF1 GIGYF2 GNB2 GRB2 HADHB INSR KCTD6 KIT KMT2B LAX1 LY6G6F MAP3K14 MSH2 PDGFRB PDHB PHAX PKM PTK2 RET RND1 RPS2 SETDB1 SHC1 TEK TLE1 TMSB4X TRIM36 ZBTB16 ZNHIT1
Entrez ID 85440 2886
HPRD ID 16833 03311
Ensembl ID ENSG00000116641 ENSG00000141738
Uniprot IDs Q96N67 A0A0S2Z4F6 Q14451
PDB IDs 6AJ4 6AJL 1MW4 1WGR 2L4K 2QMS 3PQZ 4WWQ 4X6S 5D0J 5EEL 5EEQ 5TYI 5U06 5U1Q
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?