GCM1 and CAMK1

Number of citations of the paper that reports this interaction (PubMedID 21791615)
14

Data Source:
BioGRID (enzymatic study)

		GCM1	CAMK1
Description		glial cells missing transcription factor 1	calcium/calmodulin dependent protein kinase I
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Transcription Factor Complex	Intracellular Nucleus Cytosol Postsynaptic Density Glutamatergic Synapse
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Histone Deacetylase Binding	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Gliogenesis Positive Regulation Of Transcription By RNA Polymerase II Astrocyte Fate Commitment Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Branching Involved In Labyrinthine Layer Morphogenesis Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Cell Differentiation Involved In Embryonic Placenta Development	Protein Phosphorylation Nucleocytoplasmic Transport Cell Cycle Signal Transduction Positive Regulation Of Neuron Projection Development Negative Regulation Of Protein Binding Regulation Of Protein Localization Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Protein Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Protein Export From Nucleus Regulation Of Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Dendritic Spine Development Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Protein Acetylation Regulation Of Histone H3-K9 Acetylation
Pathways			Negative regulation of NMDA receptor-mediated neuronal transmission Activation of RAC1 downstream of NMDARs Activation of RAC1 downstream of NMDARs
Drugs
Diseases
GWAS		Cerebrospinal fluid AB1-42 levels ( 26252872)
Interacting Genes		9 interacting genes: CAMK1 CREBBP DUSP23 HDAC1 HDAC3 HDAC4 HDAC5 SENP1 UBE2I	20 interacting genes: APP ATF1 CALM1 CAMKK1 CAMKK2 CCND1 CDK4 CDKN1B EIF4G3 FBXO7 GAPDH GCM1 HDAC5 HSPB1 MARK2 NOS1 PIK3R3 PPME1 PPP2CA SYN1
Entrez ID		8521	8536
HPRD ID		04757	05412
Ensembl ID		ENSG00000137270	ENSG00000134072
Uniprot IDs		Q9NP62	B0YIY3 Q14012
PDB IDs			4FG7 4FG8 4FG9 4FGB
Enriched GO Terms of Interacting Partners?
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