AJUBA and AURKAIP1

Number of citations of the paper that reports this interaction (PubMedID 13678582)
206

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		AJUBA	AURKAIP1
Description		ajuba LIM protein	aurora kinase A interacting protein 1
Image		No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus Microtubule Organizing Center Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Focal Adhesion Lamellipodium	Nucleus Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Ribosome Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Transcription Corepressor Activity Protein Binding Alpha-catenin Binding Metal Ion Binding Actin Filament Binding	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Response To Hypoxia Regulation Of Transcription, DNA-templated Cytoskeleton Organization Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Lamellipodium Assembly Regulation Of Cell Migration Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Protein Complex Assembly Negative Regulation Of Kinase Activity Cellular Protein Localization Gene Silencing By MiRNA Wound Healing, Spreading Of Epidermal Cells Negative Regulation Of Hippo Signaling Regulation Of GTPase Activity Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of MAP Kinase Activity Glycerophospholipid Biosynthetic Process Focal Adhesion Assembly Regulation Of Cellular Response To Hypoxia Positive Regulation Of Gene Silencing By MiRNA	MRNA Processing Negative Regulation Of Mitotic Nuclear Division Positive Regulation Of Proteolysis Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Regulation of PLK1 Activity at G2/M Transition Activation of anterior HOX genes in hindbrain development during early embryogenesis	Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination
Drugs
Diseases
GWAS		Insular cortex volume ( 31530798) Macular thickness ( 30535121) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Spatial processing ( 31596458)	Heel bone mineral density ( 30598549) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998) Ulcerative colitis ( 28067908)
Interacting Genes		10 interacting genes: ACTA1 AURKAIP1 AURKB BCAR1 CTNNA1 GFI1B GRB2 LATS2 LCK SLC1A2	3 interacting genes: AJUBA AURKA FAM9B
Entrez ID		84962	54998
HPRD ID		16426	16457
Ensembl ID		ENSG00000129474	ENSG00000175756
Uniprot IDs		Q96IF1	Q9NWT8
PDB IDs			3J9M 6NU2 6NU3
Enriched GO Terms of Interacting Partners?
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