RITA1 and DCP1A

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RITA1	DCP1A
Description		RBPJ interacting and tubulin associated 1	decapping mRNA 1A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome	P-body Nucleus Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Protein Binding Tubulin Binding	MRNA Binding Protein Binding Enzyme Activator Activity Hydrolase Activity Kinesin Binding Enzyme Regulator Activity Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Neurogenesis Negative Regulation Of Notch Signaling Pathway Nuclear Export	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of Catalytic Activity Regulation Of MRNA Stability Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Protein Localization To Cytoplasmic Stress Granule
Pathways			mRNA decay by 5' to 3' exoribonuclease Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Body mass index ( 26426971) Electrocardiographic traits ( 25055868) Erosive tooth wear (severe vs non-severe) ( 29898447) Heart rate ( 23583979) Spontaneous preterm birth (preterm delivery) ( 25599974)
Interacting Genes		4 interacting genes: APP DCP1A GOLGA2 HOOK2	15 interacting genes: AGO1 AGO2 DCP2 EDC3 FHL2 LSM8 MAPK3 NSMAF PAXIP1 PNRC2 RITA1 SMAD4 TTF2 UPF1 YWHAG
Entrez ID		84934	55802
HPRD ID		08606	06113
Ensembl ID		ENSG00000139405	ENSG00000272886
Uniprot IDs		A0A024RBL1 Q96K30	Q9NPI6
PDB IDs		5EG6	2WX3 4B6H
Enriched GO Terms of Interacting Partners?
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