HOPX and EPC1

Number of citations of the paper that reports this interaction (PubMedID 17192267)
24

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		HOPX	EPC1
Description		HOP homeobox	enhancer of polycomb homolog 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Nuclear Body Nuclear Membrane Piccolo NuA4 Histone Acetyltransferase Complex NuA4 Histone Acetyltransferase Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	Histone Acetyltransferase Activity Protein Binding
	Biological Process	Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation Chaperone-mediated Protein Complex Assembly	Negative Regulation Of Transcription By RNA Polymerase II Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Vascular Smooth Muscle Cell Differentiation Regulation Of Growth Histone H4 Acetylation Histone H2A Acetylation Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of G0 To G1 Transition
Pathways			HATs acetylate histones Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Systemic sclerosis ( 30247649)	Diastolic blood pressure ( 30224653) Metabolite levels ( 23823483) Platelet distribution width ( 27863252) Sexual dysfunction (female) ( 22509378)
Interacting Genes		8 interacting genes: COMT EPC1 HDAC2 HOXB9 SRF TCF12 TLX3 ZSCAN1	6 interacting genes: E2F6 HOPX KRT15 MBTD1 RINT1 TRIM27
Entrez ID		84525	80314
HPRD ID		06280	09941
Ensembl ID		ENSG00000171476	ENSG00000120616
Uniprot IDs		Q9BPY8	Q9H2F5
PDB IDs			6NFX
Enriched GO Terms of Interacting Partners?
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