STX7 and VAMP8

Number of citations of the paper that reports this interaction (PubMedID 26186194)
367

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		STX7	VAMP8
Description		syntaxin 7	vesicle associated membrane protein 8
Image		No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Lysosome Lysosomal Membrane Endosome Early Endosome Late Endosome Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane Endocytic Vesicle SNARE Complex Early Endosome Membrane Vesicle Azurophil Granule Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome Tertiary Granule	Cytoplasm Lysosomal Membrane Early Endosome Cytosol Plasma Membrane Membrane Integral Component Of Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane SNARE Complex Early Endosome Membrane Late Endosome Membrane Vesicle Azurophil Granule Membrane Specific Granule Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Tertiary Granule Membrane Mucin Granule
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding	SNAP Receptor Activity Protein Binding Chloride Channel Inhibitor Activity Syntaxin Binding
	Biological Process	Positive Regulation Of T Cell Mediated Cytotoxicity Intracellular Protein Transport Vesicle Fusion Vesicle Docking Organelle Localization Organelle Assembly Positive Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Plasma Membrane	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Post-Golgi Vesicle-mediated Transport Vesicle Fusion Protein Transport Autophagosome Membrane Docking SNARE Complex Assembly Eosinophil Degranulation Neutrophil Degranulation Viral Entry Into Host Cell Membrane Organization Mucus Secretion Autophagosome Maturation Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Secretion By Cell Positive Regulation Of Histamine Secretion By Mast Cell
Pathways			ER-Phagosome pathway trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Neutrophil degranulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Red cell distribution width ( 27863252) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Coronary artery disease ( 29212778 26343387) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Eosinophil counts ( 27863252) Myocardial infarction ( 26343387) Prostate cancer ( 21743467) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		15 interacting genes: CREB3 DNAJC5 ENTPD2 LMNA MAPK6 NAPA SNAP29 STX6 STX8 VAMP7 VAMP8 VPS11 VPS16 VPS18 VTI1B	12 interacting genes: CDC25A MLH1 NAPA SNAP23 SNAP25 STX1A STX3 STX4 STX7 UBE2G2 VAMP2 VAMP3
Entrez ID		8417	8673
HPRD ID		04449	04415
Ensembl ID		ENSG00000079950	ENSG00000118640
Uniprot IDs		O15400	B8ZZT4 Q9BV40
PDB IDs			4WY4
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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