KAT8 and MSL3

Number of citations of the paper that reports this interaction (PubMedID 20479123)
119

Data Source:
BioGRID (affinity chromatography technology, pull down)

		KAT8	MSL3
Description		lysine acetyltransferase 8	MSL complex subunit 3
Image
GO Annotations	Cellular Component	Histone Acetyltransferase Complex Kinetochore Nuclear Chromatin Nucleus Nucleoplasm Nuclear Matrix MLL1 Complex MSL Complex	Histone Acetyltransferase Complex Nucleus Nucleoplasm NuA4 Histone Acetyltransferase Complex MSL Complex
	Molecular Function	Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Acetyltransferase Activity Enzyme Binding Methylated Histone Binding Histone Binding Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Metal Ion Binding Histone Acetyltransferase Activity (H4-K16 Specific)	DNA Binding Protein Binding Methylated Histone Binding Histone Acetyltransferase Activity (H4-K16 Specific)
	Biological Process	Regulation Of Autophagy Histone Acetylation Myeloid Cell Differentiation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Chromatin Silencing Regulation Of Transcription, DNA-templated Histone Acetylation Histone Deacetylation Histone H4 Acetylation Histone H2A Acetylation Histone H4-K16 Acetylation
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Body mass index ( 25673413) Family history of Alzheimer's disease ( 30617256) Parkinson's disease ( 28892059)
Interacting Genes		12 interacting genes: ATM BAZ2A FOXP3 H4C1 KANSL1 KMT2A MSL3 PAF1 PLAU RNF2 TP53 TP53BP1	8 interacting genes: APP CDK6 H3-4 H3C1 H4-16 H4C1 KAT8 PAF1
Entrez ID		84148	10943
HPRD ID		11381	05344
Ensembl ID		ENSG00000103510	ENSG00000005302
Uniprot IDs		Q9H7Z6	Q8N5Y2
PDB IDs		2GIV 2PQ8 2Y0M 3QAH 3TOA 3TOB 4DNC 5H43 5J8C 5J8F 5WCI 6BA2 6BA4 6CT2 6OIN 6OIO 6OIP 6OIQ 6OIR	2Y0N 3OA6 3OB9
Enriched GO Terms of Interacting Partners?
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