DTNBP1 and DTNB

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vivo, in vitro)

		DTNBP1	DTNB
Description		dystrobrevin binding protein 1	dystrobrevin beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Sarcoplasm Cell Junction Axon Growth Cone Midbody Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Blood Coagulation Anterograde Axonal Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Negative Regulation Of Protein Binding Melanosome Organization Regulation Of JUN Kinase Activity Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis
Pathways		Golgi Associated Vesicle Biogenesis
Drugs
Diseases		Hermansky-Pudlak syndrome (HPS)
GWAS		Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Corneal astigmatism ( 30306274) Multiple myeloma ( 27363682) Squamous cell carcinoma ( 31174203)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Decreased low contrast letter acuity in multiple sclerosis ( 31289819) Height ( 18391951) Heschl's gyrus morphology ( 25130324) Intracranial aneurysm ( 29531279) LDL cholesterol ( 21347282) Macular thickness ( 30535121) Multiple myeloma ( 22120009 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Resistant hypertension ( 31545351) Response to platinum-based chemotherapy (cisplatin) ( 21844884) Type 2 diabetes ( 30297969) Waist circumference adjusted for body mass index ( 28552196) Working memory ( 31598132)
Interacting Genes		46 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCDC153 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 MACF1 NBEA NDN NUF2 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM9 WASHC3 ZNF490	30 interacting genes: ABI2 ABI3 BEGAIN CCDC85B CEP55 CEP63 DMD DTNBP1 GGA1 HMG20A KIF5A KIF5B KRT31 KRT40 MTUS2 NDEL1 NUP62 PPFIA1 PPFIBP2 PRTFDC1 SNTG1 SNTG2 SPZ1 TRAF2 TSACC TXLNA USHBP1 UTRN VCP ZBTB9
Entrez ID		84062	1838
HPRD ID		06190	09091
Ensembl ID		ENSG00000047579	ENSG00000138101
Uniprot IDs		A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8	B7Z202 B7Z6A9 E7EVB6 E9PEY4 O60941 Q1I0L3
PDB IDs
Enriched GO Terms of Interacting Partners?
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