RBM48 and PNP

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RBM48	PNP
Description		RNA binding motif protein 48	purine nucleoside phosphorylase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	RNA Binding Protein Binding	Nucleoside Binding Purine Nucleobase Binding Purine-nucleoside Phosphorylase Activity Drug Binding Phosphate Ion Binding Identical Protein Binding
	Biological Process		Nucleobase-containing Compound Metabolic Process Inosine Catabolic Process Purine Nucleotide Catabolic Process Nicotinamide Riboside Catabolic Process Immune Response Nucleotide Biosynthetic Process Urate Biosynthetic Process Positive Regulation Of T Cell Proliferation Response To Drug Purine-containing Compound Salvage Neutrophil Degranulation Positive Regulation Of Alpha-beta T Cell Differentiation Interleukin-2 Secretion
Pathways			Neutrophil degranulation Purine salvage Purine catabolism
Drugs			Cladribine Didanosine 8-azaguanine 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine Immucillin-G Guanine 2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One Peldesine 9-Deazainosine Guanosine Ribose-1-Phosphate 4'-Deaza-1'-Aza-2'-Deoxy-1'-(9-Methylene)-Immucillin-H, (3r,4r)-N-[9-Deazahypoxanthin-9-Yl)Methyl]-4-Hydroxymethyl-Pyrrolidin-3-Ol 3-Deoxyguanosine MT-Immucillin-H Hypoxanthine 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine Inosine 9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE
Diseases			Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Idiopathic dilated cardiomyopathy ( 29495422)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576) Interferon alpha levels in systemic lupus erythematosus ( 25338677) Menopause (age at onset) ( 26414677)
Interacting Genes		50 interacting genes: ANXA7 APLP1 BID BTBD2 C11orf49 CCDC106 CDK5RAP2 CDKN1A CDKN2C COX17 ERH FAM118B FXYD6 GADD45G GLYAT GSE1 GSTO1 HSPB1 HSPB3 ID2 KPNA2 MAFG MAP7D1 MLLT3 MNAT1 MPHOSPH6 NUDT21 OSGEP PAFAH1B3 PCDHA4 PNP PPP1R8 PRG2 PSMD11 RAB27A RFC5 RPA2 SAT1 SERPINB9 SH3GL3 SMN1 SULT1E1 TAF9 TK1 TNFSF10 TRDMT1 TRIB3 VIM WDR33 ZNF24	11 interacting genes: APLP1 CCDC90B LRIF1 NCALD NOS1AP RBM48 TFAM TFB2M TP53 UCHL5 ZHX1
Entrez ID		84060	4860
HPRD ID		13173	01247
Ensembl ID		ENSG00000127993	ENSG00000198805
Uniprot IDs		Q5RL73	P00491 V9HWH6
PDB IDs			1M73 1PF7 1PWY 1RCT 1RFG 1RR6 1RSZ 1RT9 1ULA 1ULB 1V2H 1V3Q 1V41 1V45 1YRY 2A0W 2A0X 2A0Y 2OC4 2OC9 2ON6 2Q7O 3BGS 3D1V 3GB9 3GGS 3INY 3K8O 3K8Q 3PHB 4EAR 4EB8 4ECE 4GKA 5ETJ 5UGF
Enriched GO Terms of Interacting Partners?
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