CASP2 and NOL3

Number of citations of the paper that reports this interaction (PubMedID 9560245)
77

Data Source:
HPRD (in vivo)

		CASP2	NOL3
Description		caspase 2	nucleolar protein 3
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Membrane	Cell Nucleolus Mitochondrion Cytosol Membrane Sarcoplasmic Reticulum
	Molecular Function	Cysteine-type Endopeptidase Activity Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis	RNA Binding Calcium Ion Binding Protein Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Caspase Binding
	Biological Process	Luteolysis Neural Retina Development Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Brain Development Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Processing Ectopic Germ Cell Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Signaling Pathway	MRNA Splice Site Selection Apoptotic Process RNA Splicing Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Apoptotic Process Protein Complex Oligomerization Negative Regulation Of Release Of Cytochrome C From Mitochondria Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		NOD1/2 Signaling Pathway NADE modulates death signalling TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS
Interacting Genes		29 interacting genes: ADCYAP1 BID CASP10 CASP14 CASP3 CASP7 CASP8 CCND3 CFLAR CRADD CSNK2A1 DCTN1 DSP EEF1A1 GOLGA3 GRB2 KPNA2 MDM2 MZB1 NLRP1 NOD1 NOL3 PIDD1 RAI1 RB1 RPL30 RXRA SUMO1 UBE2I	15 interacting genes: BAX CASP2 CASP8 CSNK2A1 ETNK2 FADD NIF3L1 POT1 SIRPA SRSF9 TERF1 TERF2IP TFPT TINF2 VASP
Entrez ID		835	8996
HPRD ID		02800	05572
Ensembl ID		ENSG00000106144	ENSG00000140939
Uniprot IDs		A0A087WYM1 A0A0S2Z3H1 D3DXD9 P42575	O60936 Q5TZN6
PDB IDs		1PYO 2P2C 3R5J 3R6G 3R6L 3R7B 3R7N 3R7S 3RJM 6GKF 6GKG	4UZ0
Enriched GO Terms of Interacting Partners?
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