GFI1B and PDE4DIP

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GFI1B	PDE4DIP
Description		growth factor independent 1B transcriptional repressor	phosphodiesterase 4D interacting protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Plasma Membrane Nuclear Matrix	Nucleus Cytoplasm Golgi Apparatus Centrosome Myofibril
	Molecular Function	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding	Protein Binding Enzyme Binding Molecular Adaptor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Regulation Of Transcription, DNA-templated Multicellular Organism Development Regulation Of Gene Expression Regulation Of Hemopoiesis Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cellular Protein-containing Complex Assembly Regulation Of Golgi Organization
Pathways
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 27863252) Cardiometabolic and hematological traits ( 27668658) Eosinophil counts ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Granulocyte count ( 27863252) High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Mean platelet volume ( 27863252) Myeloid white cell count ( 27863252) Neutrophil percentage of granulocytes ( 27863252) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Red cell distribution width ( 27863252 28957414) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252) Sum eosinophil basophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 27863252) White blood cell count (basophil) ( 27863252)	Capecitabine sensitivity ( 22864933)
Interacting Genes		71 interacting genes: ACTN1 AGRN AJUBA ANKS3 ATXN2 BABAM2 BECN1 BEGAIN BEND5 BRCA1 CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GPAT4 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TLE5 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3	76 interacting genes: ADH1B AEN ANKRD11 ARNT2 BYSL C1orf109 CCDC146 CCDC198 CDC5L CDKN1A CHCHD3 CHD1L EGR2 EIF4E2 FAM161A FAM74A4 FCHSD2 FES FHL1 GADD45G GBE1 GFI1B GNRHR2 GOLGA5 GOLGA8EP GOLGA8F HAUS1 IMMT ITSN2 KDM1A KLC3 KLC4 KRAS KRT1 KRT18 KRT31 LAMTOR3 LENG1 LMO4 MIF4GD MTUS2 NAA10 NEFL NEK2 OSGEP PDE4D PEA15 PFDN1 PIAS4 PPP1R18 PRNP PRPF31 RBM8A RTP5 SCNM1 SDCBP SH2D4A SHFL SMN1 SNCA TEAD4 TFIP11 THRB TK1 TMOD4 TNIK TRAF4 UTP14C VAC14 ZBTB38 ZDHHC17 ZFYVE21 ZNF408 ZNF512B ZNF581 ZSCAN26
Entrez ID		8328	9659
HPRD ID		05088	10482
Ensembl ID		ENSG00000165702	ENSG00000178104
Uniprot IDs		A0A024R8F3 Q5VTD9	A0A075B749 A0A087WYE4 Q5VU43
PDB IDs
Enriched GO Terms of Interacting Partners?
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