TLR10 and PTPN6

  • Number of citations of the paper that reports this interaction (PubMedID 16482509)
  • 21
  • Data Source:
  • HPRD (two hybrid)

TLR10

PTPN6

Description toll like receptor 10 protein tyrosine phosphatase non-receptor type 6
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Allergic disease (asthma, hay fever or eczema) ( 29785011)
  • Allergic rhinitis ( 30013184)
  • Allergic sensitization ( 23817571)
  • Asthma ( 31361310 31619474)
  • Asthma (age of onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433)
  • Asthma or allergic disease (pleiotropy) ( 29785011)
  • Diabetes in response to antihypertensive drug treatment (treatment strategy interaction) ( 27670767)
  • Endometriosis or endometrial cancer (pleiotropy) ( 29608257)
  • Helicobacter pylori serologic status ( 23652523)
  • Limited cutaneous systemic scleroderma ( 29293537)
  • Self-reported allergy ( 23817569)
  • Systemic sclerosis (anti-topoisomerase-positive) ( 29293537)
  • Mean corpuscular hemoglobin concentration ( 29403010)
  • Red blood cell fatty acid levels ( 25500335)
Interacting Genes 11 interacting genes: CAT ECH1 F8A1 FLNA FUT7 GLDC LUC7L3 MYD88 PTPN6 TLR1 TLR2 114 interacting genes: AATK ABL1 ACTN1 ACTN4 BCR BLNK BTLA CAV1 CBL CCDC88A CD22 CD247 CD300LF CD33 CD5 CD72 CD79A CD79B CDK1 CEACAM1 CLEC4A CSF2RB CTNNB1 CTNND1 CUZD1 CXCR4 DOK1 EGFR EPOR ERBB2 ERBB3 ERBB4 ESR1 FAS FCGR2B FCRL3 FGFR4 FHL3 FLT3 GAB2 GHR GRB2 HOXA10 IFNAR1 IGF1R IL2RB IL4R IL6ST INSR IRS2 IRS4 JAK1 JAK2 JAK3 KDR KHDRBS1 KIR2DL3 KIR2DL5A KIT KLRA1P KLRB1 KLRC1 LAIR1 LAT LCK LCP2 LIFR LILRB2 LILRB4 LMTK2 LYN MPIG6B MS4A2 MYH9 NOS1 OLIG1 PAG1 PDGFRB PECAM1 PIK3R1 PILRA PILRB PLCG2 PRKCA PRKCD PTK2B PTK7 PTPN11 PTPRC ROR1 ROR2 ROS1 SHC1 SIGLEC10 SIGLEC11 SIGLEC12 SIRPA SLAMF6 SOS1 SPATA2 SRC SSTR2 STAT5B STAT6 SYK TFG TLR10 TMEM62 TNFRSF1A TRAF6 TREML1 TYK2 VAV1 ZAP70
Entrez ID 81793 5777
HPRD ID 05884 01475
Ensembl ID ENSG00000174123 ENSG00000111679
Uniprot IDs A0A024R9W4 Q9BXR5 P29350 Q53XS4
PDB IDs 2J67 1FPR 1GWZ 1X6C 2B3O 2RMX 2YU7 3PS5 4GRY 4GRZ 4GS0 4HJP 4HJQ
Enriched GO Terms of Interacting Partners?
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