CAMK2D and BANP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CAMK2D	BANP
Description		calcium/calmodulin dependent protein kinase II delta	BTG3 associated nuclear protein
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Calcium- And Calmodulin-dependent Protein Kinase Complex Membrane Endocytic Vesicle Membrane Sarcoplasmic Reticulum Membrane Sarcolemma Neuron Projection	Nucleoplasm Nuclear Body
	Molecular Function	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Sodium Channel Inhibitor Activity Titin Binding Identical Protein Binding Protein Homodimerization Activity Ion Channel Binding	P53 Binding DNA Binding Protein Binding
	Biological Process	Regulation Of Cell Growth Regulation Of The Force Of Heart Contraction Regulation Of Membrane Depolarization Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Regulation Of Heart Contraction Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Endoplasmic Reticulum Calcium Ion Homeostasis Protein Autophosphorylation Relaxation Of Cardiac Muscle Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Interferon-gamma-mediated Signaling Pathway Regulation Of Cellular Localization Cellular Response To Calcium Ion Cardiac Muscle Cell Contraction Regulation Of Heart Rate By Cardiac Conduction Regulation Of Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Cellular Response To Heat Regulation Of Histone Deacetylase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Relaxation Of Cardiac Muscle Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of Sodium Ion Transmembrane Transporter Activity	Chromatin Organization Cell Cycle Multicellular Organism Development Protein Localization To Nucleus Negative Regulation Of Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction By P53 Class Mediator
Pathways		CaMK IV-mediated phosphorylation of CREB HSF1-dependent transactivation Trafficking of AMPA receptors Unblocking of NMDA receptors, glutamate binding and activation Unblocking of NMDA receptors, glutamate binding and activation Ras activation upon Ca2+ influx through NMDA receptor Phase 0 - rapid depolarisation Ion homeostasis RAF activation RAF/MAP kinase cascade Signaling by moderate kinase activity BRAF mutants Signaling by BRAF and RAF fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Interferon gamma signaling Regulation of MECP2 expression and activity Ion transport by P-type ATPases Assembly and cell surface presentation of NMDA receptors Negative regulation of NMDA receptor-mediated neuronal transmission Long-term potentiation Signaling downstream of RAS mutants	Regulation of TP53 Activity through Association with Co-factors
Drugs		[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILE (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Chronic lymphocytic leukemia ( 28165464 24292274) Chronotype ( 30696823) Hip circumference adjusted for BMI ( 28552196) Ischemic stroke (small-vessel) ( 29531354) Non-small cell lung cancer (survival) ( 25145502) P wave duration ( 28794112) Parkinson's disease ( 28892059) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) PR interval ( 30046033) T wave morphology restitution during recovery from exercise ( 31607149) T wave morphology restitution during recovery from exercise (MTAG) ( 31607149) White matter integrity (bipolar disorder risk interaction) ( 23218918)	Central corneal thickness ( 28171582 20719862) Corneal structure ( 23291589) Intraocular pressure ( 29235454) Systolic blood pressure ( 30224653)
Interacting Genes		28 interacting genes: ACTN2 ARL2BP BANP CAMK2B CD5 CREM DNAL4 EPHA10 ERCC8 FAM171B FKBP1B FNDC3B FXR2 GRIN2B HNMT IFNGR2 MOAP1 MRPL11 RPS18 RPS4X SMARCB1 SPATA24 SRPK1 STAT1 TNPO2 TTC5 VIM WASF3	95 interacting genes: ADAM15 AFG1L ALAS2 BAG5 BLZF1 BTG3 C1orf94 C22orf39 CAMK2D CCDC26 CDX4 CEP76 CFAP206 COL10A1 CRX CYTOR DCDC2B DLX3 DNAJA4 EPHA10 FAM117B FAM120C FAM71C FAM90A1 FHL2 FHL5 FOXM1 FOXR1 GFM2 HMGB3P1 HNRNPLL HSFY1 ISCU L3MBTL3 LENG1 LGALS14 LINC01547 LMO2 LMO3 LMO4 LSM2 MAP2K1 MAPK1 MAX MDFI MEOX1 MEOX2 MIR4435-2HG MRPL28 MRRF MVP NEDD9 NMNAT1 NRIP2 PHF21A PHF21B PID1 PIM1 PML POGZ POLDIP3 POLR2L PPIB PPIC PPIF PRKAB2 PRKCH PRPF39 PRR20A PSMD9 RAB3IP RBM39 RBPMS REL RIMS3 SH3RF2 SLC16A3 SNRPB SP2 SP4 SPACA6 TERF2 TERF2IP TNXB TOX4 TP53 TRAF2 TRAF4 TROAP XAGE1B ZC2HC1C ZMIZ2 ZNF471 ZNF488 ZNF581
Entrez ID		817	54971
HPRD ID		09653	16538
Ensembl ID		ENSG00000145349	ENSG00000172530
Uniprot IDs		D6R938 E9PBG7 E9PF82 Q13557	A0A0S2Z5C2 A0A0S2Z5G4 A0A0S2Z5M2 B3KM38 B4DE54 Q8N9N5 Q9NSS6
PDB IDs		2VN9 2W2C 2WEL 3GP2 5VLO 6AYW
Enriched GO Terms of Interacting Partners?
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