ALX1 and IPO13

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		ALX1	IPO13
Description		ALX homeobox 1	importin 13
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Golgi Apparatus Nuclear Body	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Protein Homodimerization Activity	Protein Binding Ran GTPase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cartilage Condensation Neural Crest Cell Migration Neural Tube Closure Transcription By RNA Polymerase II Multicellular Organism Development Anterior/posterior Pattern Specification Positive Regulation Of Epithelial To Mesenchymal Transition Embryonic Limb Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Roof Of Mouth Development	Protein Import Into Nucleus
Pathways
Drugs
Diseases		Frontonasal dysplasia
GWAS		Bone mineral density (Ward's triangle area) ( 27397699) Lung function (FEV1) ( 30061609) Lung function (FVC) ( 30061609) Nonsyndromic cleft lip ( 31609978) Nose size ( 27182965)	Autism spectrum disorder or schizophrenia ( 28540026)
Interacting Genes		5 interacting genes: ALX4 CREBBP EP300 IPO13 SRA1	14 interacting genes: ALX1 CRX EIF1AX GK MAGOH NUP50 PAX3 PAX6 PBX4 PITX1 RAN RBM8A RPL5 UBE2I
Entrez ID		8092	9670
HPRD ID		03316	13742
Ensembl ID		ENSG00000180318	ENSG00000117408
Uniprot IDs		Q15699 V9HWA7	O94829
PDB IDs			2X19 2XWU 3ZJY
Enriched GO Terms of Interacting Partners?
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