TSEN2 and RANBP10

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		TSEN2	RANBP10
Description		tRNA splicing endonuclease subunit 2	RAN binding protein 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleoplasm Nucleolus Centrosome Cytosol	Ubiquitin Ligase Complex Nucleus Cytosol
	Molecular Function	TRNA-intron Endonuclease Activity Nucleic Acid Binding Protein Binding Lyase Activity	Protein Binding
	Biological Process	TRNA-type Intron Splice Site Recognition And Cleavage TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Processing RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways		tRNA processing in the nucleus	MET activates RAS signaling
Drugs
Diseases		Pontocerebellar hypoplasia
GWAS		Systemic lupus erythematosus ( 28714469) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Empathy quotient ( 29527006) HDL cholesterol ( 25961943) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Schizophrenia ( 25056061 29483656)
Interacting Genes		3 interacting genes: NUP210 RANBP10 TSEN54	12 interacting genes: CACHD1 CNTNAP4 IGSF1 MAEA MEGF10 MET NEDD4 NEDD4L PRKCG RAN THSD7B TSEN2
Entrez ID		80746	57610
HPRD ID		10576	15207
Ensembl ID		ENSG00000154743	ENSG00000141084
Uniprot IDs		Q8NCE0	B3KP49 Q6VN20 R4GMX8
PDB IDs
Enriched GO Terms of Interacting Partners?
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