SCUBE1 and PMPCA

		SCUBE1	PMPCA
Description		signal peptide, CUB domain and EGF like domain containing 1	peptidase, mitochondrial processing subunit alpha
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Cell Surface Extrinsic Component Of Plasma Membrane	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding	Endopeptidase Activity Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Inflammatory Response Signal Transduction Adult Heart Development Blood Coagulation Post-embryonic Development Extracellular Matrix Disassembly Endothelial Cell Differentiation Positive Regulation Of Smoothened Signaling Pathway	Proteolysis Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport
Pathways		Degradation of the extracellular matrix	Mitochondrial protein import Processing of SMDT1
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Molar-incisor hypomineralization ( 23918034) Response to fenofibrate (adiponectin levels) ( 23149075) Waist circumference adjusted for body mass index ( 28552196)	Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		3 interacting genes: PMPCA SCUBE2 SCUBE3	13 interacting genes: ASS1 AVEN BMPR2 KIF2C NDOR1 NPSR1 NSMF OLFM1 PCDHB4 PMPCB SCUBE1 SKIV2L UBAC1
Entrez ID		80274	23203
HPRD ID		18029	07500
Ensembl ID		ENSG00000159307	ENSG00000165688
Uniprot IDs		A0JP65 Q6ZS56 Q86TI6 Q8IWY4	Q10713
PDB IDs
Enriched GO Terms of Interacting Partners?
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