PTGES2 and RPL27A

		PTGES2	RPL27A
Description		prostaglandin E synthase 2	ribosomal protein L27a
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Cell Nucleus Mitochondrion Cytosol Integral Component Of Membrane Azurophil Granule Lumen Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Cytosol Membrane Cytosolic Large Ribosomal Subunit
	Molecular Function	DNA Binding Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Lyase Activity Heme Binding Glutathione Binding Prostaglandin-E Synthase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Cyclooxygenase Pathway Electron Transport Chain Neutrophil Degranulation Cell Redox Homeostasis Positive Regulation Of Transcription, DNA-templated	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Neutrophil degranulation	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Penile cancer
GWAS		Body mass index ( 26426971)	Body mass index ( 26426971 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Obesity ( 23563607)
Interacting Genes		8 interacting genes: C1orf189 C9orf78 CEBPB COL23A1 CRY2 EXOSC10 PTGFR RPL27A	6 interacting genes: GTF2F2 PEX6 PRKACB PTEN PTGES2 SIAH1
Entrez ID		80142	6157
HPRD ID		07458	04701
Ensembl ID		ENSG00000148334	ENSG00000166441
Uniprot IDs		A6NHH0 B3KPZ2 B4DWP1 Q9H7Z7	P46776
PDB IDs			4BXF 4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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