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UBXN8 and SFRP1
UBXN8
SFRP1
Description
UBX domain protein 8
secreted frizzled related protein 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Nucleolus
Endoplasmic Reticulum
Integral Component Of Endoplasmic Reticulum Membrane
Extracellular Region
Extracellular Space
Cytosol
Plasma Membrane
Cell Surface
Collagen-containing Extracellular Matrix
Extracellular Exosome
Molecular Function
Protein Binding
Cysteine-type Endopeptidase Activity
Frizzled Binding
Protein Binding
Drug Binding
Heparin Binding
Wnt-protein Binding
Identical Protein Binding
Biological Process
Single Fertilization
Ubiquitin-dependent ERAD Pathway
Osteoblast Differentiation
Ureteric Bud Development
Positive Regulation Of Cell-matrix Adhesion
Hematopoietic Progenitor Cell Differentiation
Proteolysis
Positive Regulation Of Cell Proliferation
Negative Regulation Of Cell Proliferation
Male Gonad Development
Female Gonad Development
Cellular Response To Starvation
Dorsal/ventral Axis Specification
Regulation Of Cell Cycle Process
Negative Regulation Of Gene Expression
Negative Regulation Of Epithelial To Mesenchymal Transition
Regulation Of Neuron Projection Development
Neural Crest Cell Fate Commitment
Response To Organic Cyclic Compound
Positive Regulation Of Wnt Signaling Pathway
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Ossification
Positive Regulation Of Cell Growth
Negative Regulation Of Cell Growth
Negative Regulation Of Cell Migration
Negative Regulation Of BMP Signaling Pathway
Negative Regulation Of Osteoblast Proliferation
Somatic Stem Cell Population Maintenance
Non-canonical Wnt Signaling Pathway
Response To Drug
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of JUN Kinase Activity
Positive Regulation Of GTPase Activity
Cellular Response To Fibroblast Growth Factor Stimulus
Stromal-epithelial Cell Signaling Involved In Prostate Gland Development
Negative Regulation Of B Cell Differentiation
Positive Regulation Of Fat Cell Differentiation
Negative Regulation Of Osteoblast Differentiation
Negative Regulation Of Osteoclast Differentiation
Regulation Of Angiogenesis
Positive Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Insulin Secretion
Negative Regulation Of Bone Remodeling
Negative Regulation Of Fibroblast Proliferation
Digestive Tract Morphogenesis
Positive Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Peptidyl-tyrosine Phosphorylation
Positive Regulation Of Stress Fiber Assembly
Positive Regulation Of Focal Adhesion Assembly
Canonical Wnt Signaling Pathway
Hematopoietic Stem Cell Differentiation
Bone Trabecula Formation
Prostate Epithelial Cord Arborization Involved In Prostate Glandular Acinus Morphogenesis
Regulation Of Branching Involved In Prostate Gland Morphogenesis
Negative Regulation Of Androgen Receptor Signaling Pathway
Cellular Response To Vitamin D
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Growth Factor Stimulus
Cellular Response To Prostaglandin E Stimulus
Cellular Response To Estrogen Stimulus
Cellular Response To Estradiol Stimulus
Cellular Response To Hypoxia
Cellular Response To X-ray
Cellular Response To Heparin
Dopaminergic Neuron Differentiation
Cellular Response To Transforming Growth Factor Beta Stimulus
Cellular Response To BMP Stimulus
Negative Regulation Of Canonical Wnt Signaling Pathway
Planar Cell Polarity Pathway Involved In Neural Tube Closure
Wnt Signaling Pathway Involved In Somitogenesis
Convergent Extension Involved In Somitogenesis
Positive Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Midbrain Dopaminergic Neuron Differentiation
Negative Regulation Of Planar Cell Polarity Pathway Involved In Axis Elongation
Positive Regulation Of Non-canonical Wnt Signaling Pathway
Negative Regulation Of Wnt Signaling Pathway Involved In Dorsal/ventral Axis Specification
Negative Regulation Of Canonical Wnt Signaling Pathway Involved In Controlling Type B Pancreatic Cell Proliferation
Negative Regulation Of Fibroblast Apoptotic Process
Positive Regulation Of Fibroblast Apoptotic Process
Pathways
TCF dependent signaling in response to WNT
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
Drugs
Diseases
GWAS
Anti-saccade response (
29064472
)
Blood protein levels (
30072576
29875488
)
Refractive astigmatism (
30306274
)
Interacting Genes
6 interacting genes:
ADRB3
C8orf86
DCTN6
RBPMS
SFRP1
WRN
8 interacting genes:
FZD6
KIAA1522
PPP1CA
PPP1CC
UBXN8
WNT1
WNT2
WNT4
Entrez ID
7993
6422
HPRD ID
03692
09165
Ensembl ID
ENSG00000104691
ENSG00000104332
Uniprot IDs
B4DKK1
O00124
Q8N474
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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