CPSF7 and SEC23B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CPSF7	SEC23B
Description		cleavage and polyadenylation specific factor 7	SEC23 homolog B, COPII coat complex component
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	RNA Binding Protein Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization Pre-mRNA Cleavage Required For Polyadenylation MRNA Alternative Polyadenylation Messenger Ribonucleoprotein Complex Assembly	Intracellular Protein Transport Positive Regulation Of GTPase Activity Cargo Loading Into COPII-coated Vesicle
Pathways		mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS
Interacting Genes		25 interacting genes: APBB1 ARMC7 ATXN1 CCDC86 CLK2 CSNK2A1 DVL2 EPM2AIP1 EWSR1 GCC1 ITCH NCK2 NUDT21 PRMT2 RBM10 RUNX1T1 SEC23B SMAD3 SNRNP25 SORBS3 SRPK2 TLE5 U2AF2 WBP4 WWOX	21 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 SEC24C SEC24D SKP1 SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1
Entrez ID		79869	10483
HPRD ID		16906	11543
Ensembl ID		ENSG00000149532	ENSG00000101310
Uniprot IDs		B4DGF8 Q8N684	A0A2R8YFH5 Q15437
PDB IDs		3N9U
Enriched GO Terms of Interacting Partners?
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