FAM118B and TMSB4X

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		FAM118B	TMSB4X
Description		family with sequence similarity 118 member B	thymosin beta 4 X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Cajal Body	Extracellular Region Cell Nucleus Cytoplasm Cytosol Cytoskeleton Platelet Alpha Granule Lumen
	Molecular Function	Protein Binding	RNA Binding Actin Monomer Binding Protein Binding Enzyme Binding
	Biological Process	Cajal Body Organization	Platelet Degranulation Actin Filament Organization Cytoplasmic Sequestering Of NF-kappaB Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Tumor Necrosis Factor-mediated Signaling Pathway Sequestering Of Actin Monomers Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Inflammatory Response Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of NIK/NF-kappaB Signaling Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proton-transporting ATP Synthase Activity, Rotational Mechanism Negative Regulation Of Interleukin-8 Secretion Positive Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of ATP Biosynthetic Process
Pathways			Platelet degranulation
Drugs
Diseases
GWAS			Asthma ( 30929738) Asthma (childhood onset) ( 30929738)
Interacting Genes		26 interacting genes: BAG5 CEP126 CEP70 CTSB FAM118A FAM20C GNB2 ING5 ITFG1 MCM3AP MED31 NGEF QARS1 RASGRP2 RBM48 SDCBP SEMA5B SETDB1 SHC1 SPRED1 SUMO1 SUMO1P1 TMSB4X VIM ZNF235 ZNF746	29 interacting genes: ACTA1 ACTA2 ACTB ACTG1 ALAS1 ANXA7 APLP1 CDKN1A FAM118B GRB7 IGSF21 ILK KRT13 KRT15 KRT31 KRT40 LIMS1 PNMA1 PPP4C RAD21 RBPMS SCHIP1 SMN1 TAF1D TGM2 TK1 TRIM23 TRIM27 TRIP6
Entrez ID		79607	7114
HPRD ID		07952	02153
Ensembl ID		ENSG00000197798	ENSG00000205542
Uniprot IDs		A0A024R3L8 J3KP39 Q9BPY3	A2VCK8 P62328 Q0P5T0
PDB IDs			1UY5 3TU5 4PL7 4PL8
Enriched GO Terms of Interacting Partners?
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