FBXL15 and RORC

Number of citations of the paper that reports this interaction (PubMedID 23555304)
16

Data Source:
BioGRID (two hybrid)

		FBXL15	RORC
Description		F-box and leucine rich repeat protein 15	RAR related orphan receptor C
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol SCF Ubiquitin Ligase Complex	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Body
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coactivator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Steroid Hormone Receptor Activity Nuclear Receptor Activity Protein Binding Oxysterol Binding Zinc Ion Binding Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Dorsal/ventral Pattern Formation Protein Ubiquitination Bone Mineralization Positive Regulation Of BMP Signaling Pathway SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Xenobiotic Metabolic Process Regulation Of Glucose Metabolic Process Regulation Of Steroid Metabolic Process Cytokine-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Circadian Regulation Of Gene Expression Cellular Response To Sterol Positive Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Adipose Tissue Development Regulation Of Transcription Involved In Cell Fate Commitment T-helper 17 Cell Differentiation
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Nuclear Receptor transcription pathway Interleukin-4 and Interleukin-13 signaling
Drugs
Diseases
GWAS		Prostate cancer ( 23535732) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 28067908) Depressive symptoms (SSRI exposure interaction) ( 25649181) Inflammatory bowel disease ( 28067908 23128233) Ulcerative colitis ( 28067908)
Interacting Genes		6 interacting genes: CSNK2B DELEC1 HNRNPD RORC SMURF1 UBC	24 interacting genes: ARNTL2 BHLHE41 CHD4 CIPC CLOCK CSNK1E DELEC1 EIF4EBP1 EVI2A FBXL15 NCOA6 NPAS2 NR1D2 PER2 PPP1CA PPP1CB PPP1CC PPP2CA PPP2R1A PPP2R1B PPP2R5D PPP2R5E PSMC5 RORB
Entrez ID		79176	6097
HPRD ID		18876	04250
Ensembl ID		ENSG00000107872	ENSG00000143365
Uniprot IDs		Q9H469	F1D8P6 P51449 Q6I9R9
PDB IDs			3B0W 3KYT 3L0J 3L0L 4NB6 4NIE 4QM0 4S14 4WLB 4WPF 4WQP 4XT9 4YMQ 4YPQ 4ZJR 4ZJW 4ZOM 5APH 5APJ 5APK 5AYG 5C4O 5C4S 5C4T 5C4U 5EJV 5ETH 5G42 5G43 5G44 5G45 5G46 5IXK 5IZ0 5K38 5K3L 5K3M 5K3N 5K6E 5K74 5LWP 5M96 5NI5 5NI7 5NI8 5NIB 5NTI 5NTK 5NTN 5NTP 5NTQ 5NTW 5NU1 5UFO 5UFR 5UHI 5VB3 5VB5 5VB6 5VB7 5VQK 5VQL 5W4R 5W4V 5X8Q 5YP5 5YP6 5ZA1 6A22 6B30 6B31 6B33 6BN6 6BR2 6BR3 6CN5 6CN6 6CVH 6E3E 6E3G 6ESN 6FGQ 6FZU 6G05 6G07 6IVX 6J1L 6NAD 6NWS 6NWT 6NWU 6O98 6P9F 6Q2W 6Q6M 6Q6O 6Q7A 6Q7H 6R7A 6R7J 6R7K 6U25
Enriched GO Terms of Interacting Partners?
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