CENPO and ERI3

Number of citations of the paper that reports this interaction (PubMedID 19447967)
15

Data Source:
BioGRID (two hybrid)

		CENPO	ERI3
Description		centromere protein O	ERI1 exoribonuclease family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Kinetochore Nucleoplasm Cytosol Nuclear Body Mis6-Sim4 Complex
	Molecular Function	Protein Binding	3'-5'-exoribonuclease Activity RNA Binding Metal Ion Binding
	Biological Process	CENP-A Containing Nucleosome Assembly	Exonucleolytic Trimming To Generate Mature 3'-end Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) DNA Catabolic Process, Exonucleolytic
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat mass ( 28552196) Body mass index ( 26426971 29273807) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Cognitive function ( 28093568) Coronary artery disease ( 29212778) Height ( 28552196 25282103 23563607) Multiple sclerosis ( 24076602) Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Trunk fat mass ( 28552196) Type 1 diabetes ( 21980299)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		4 interacting genes: CEP170P1 ERI3 FOS NECAB2	4 interacting genes: CENPO CPEB2 HOOK1 PRNP
Entrez ID		79172	79033
HPRD ID		14414	15175
Ensembl ID		ENSG00000138092	ENSG00000117419
Uniprot IDs		Q9BU64	B4DEX5 B4DN03 O43414
PDB IDs			2XRI
Enriched GO Terms of Interacting Partners?
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