MBOAT7 and UNC93B1

Number of citations of the paper that reports this interaction (PubMedID 21903422)
114

Data Source:
BioGRID (pull down)

		MBOAT7	UNC93B1
Description		membrane bound O-acyltransferase domain containing 7	unc-93 homolog B1, TLR signaling regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondria-associated ER Membrane	Golgi Membrane Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Early Phagosome
	Molecular Function	1-acylglycerol-3-phosphate O-acyltransferase Activity Protein Binding 2-acylglycerol-3-phosphate O-acyltransferase Activity Lysophospholipid Acyltransferase Activity	Protein Binding Toll-like Receptor Binding
	Biological Process	Phospholipid Biosynthetic Process Ventricular System Development Layer Formation In Cerebral Cortex Phosphatidylinositol Acyl-chain Remodeling	Toll-like Receptor Signaling Pathway Adaptive Immune Response Intracellular Protein Transport Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 7 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Innate Immune Response Defense Response To Virus
Pathways		Acyl chain remodelling of PI	Trafficking and processing of endosomal TLR UNC93B1 deficiency - HSE
Drugs
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Cirrhosis (alcohol related) ( 26482880) Obesity-related traits ( 23251661) Phosphatidylinositol levels ( 31551469)
Interacting Genes		4 interacting genes: MAPK6 STING1 UBC UNC93B1	2 interacting genes: CLPTM1 MBOAT7
Entrez ID		79143	81622
HPRD ID		06925	12191
Ensembl ID		ENSG00000125505	ENSG00000110057
Uniprot IDs		Q96N66	Q9H1C4
PDB IDs
Enriched GO Terms of Interacting Partners?
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