AHNAK and KLHL40

Number of citations of the paper that reports this interaction (PubMedID 24960163)
34

Data Source:
BioGRID (two hybrid)

		AHNAK	KLHL40
Description		AHNAK nucleoprotein	kelch like family member 40
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GO Annotations	Cellular Component	Nucleus Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Membrane T-tubule Vesicle Sarcolemma Costamere Cell-cell Contact Zone Membrane Raft Extracellular Exosome	Cytoplasm Cul3-RING Ubiquitin Ligase Complex A Band I Band
	Molecular Function	RNA Binding Protein Binding S100 Protein Binding Cadherin Binding Structural Molecule Activity Conferring Elasticity	Protein Binding
	Biological Process	Regulation Of RNA Splicing Regulation Of Voltage-gated Calcium Channel Activity	Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Skeletal Muscle Fiber Development Skeletal Muscle Fiber Differentiation
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 28714976) Blond vs. brown/black hair color ( 30531825) Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Gamma glutamyl transferase levels ( 29403010) Heel bone mineral density ( 30598549 28869591) Lung function (FEV1) ( 28166213) Plasma omega-6 polyunsaturated fatty acid levels (arachidonic acid) ( 24823311) Serum alkaline phosphatase levels ( 31666285) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: AKT1 CCDC86 CDKN2A EGFR KLHL40 NOL9 POT1 S100B SUMO2 XRCC4	9 interacting genes: AHNAK C7orf31 CC2D1B LMOD3 LRRC29 REL TASOR2 VDAC1 ZBED1
Entrez ID		79026	131377
HPRD ID		14684	11058
Ensembl ID		ENSG00000124942	ENSG00000157119
Uniprot IDs		B4DTV0 Q09666 Q9BVU3	A8K5H9 Q2TBA0
PDB IDs		4DRW 4FTG 4HRG	4ASC
Enriched GO Terms of Interacting Partners?
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