CRELD1 and GDF9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CRELD1	GDF9
Description		cysteine rich with EGF like domains 1	growth differentiation factor 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Collagen-containing Extracellular Matrix	Extracellular Space Cytoplasm
	Molecular Function	Protein Disulfide Isomerase Activity Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding	Cytokine Activity Growth Factor Activity
	Biological Process	Endocardial Cushion Development Cardiac Septum Development	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion
Pathways
Drugs
Diseases		Atrioventricular septal defect; Atrioventricular canal defect
GWAS		Blood protein levels ( 30072576 29875488)	Asthma ( 31619474)
Interacting Genes		12 interacting genes: ATP5MF COPS6 EEF1G EIF6 GDF9 KAT5 MAP3K1 MTNR1B POLA2 PTN SETDB1 ZNF408	45 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3
Entrez ID		78987	2661
HPRD ID		06206	03560
Ensembl ID		ENSG00000163703	ENSG00000164404
Uniprot IDs		A0A024R2G1 Q96HD1	B4DXG3 O60383
PDB IDs
Enriched GO Terms of Interacting Partners?
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