EVI5 and BIRC5

Number of citations of the paper that reports this interaction (PubMedID 16764853)
9

Data Source:
BioGRID (pull down)

		EVI5	BIRC5
Description		ecotropic viral integration site 5	baculoviral IAP repeat containing 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Microtubule Organizing Center Spindle Cytosol	Nuclear Chromosome Chromosome, Centromeric Region Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Spindle Microtubule Midbody Chromosome Passenger Complex
	Molecular Function	GTPase Activator Activity Protein Binding Rab GTPase Binding	Protein Binding Microtubule Binding Ran GTPase Binding Enzyme Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Metal Ion Binding Chaperone Binding
	Biological Process	Intracellular Protein Transport Cell Cycle Retrograde Transport, Endosome To Golgi Positive Regulation Of GTPase Activity Cell Division Activation Of GTPase Activity Regulation Of Cilium Assembly	Protein Phosphorylation Apoptotic Process Chromosome Segregation Sensory Perception Of Sound Positive Regulation Of Cell Proliferation Cytokine-mediated Signaling Pathway Protein-containing Complex Localization Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transcription, DNA-templated Cell Division Mitotic Spindle Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion SUMOylation of DNA replication proteins RHO GTPases Activate Formins Interleukin-4 and Interleukin-13 signaling TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Mitotic Prometaphase Neddylation EML4 and NUDC in mitotic spindle formation
Drugs			Reserpine Berberine LY2181308
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma or allergic disease (pleiotropy) ( 29785011) Cholesterol, total ( 24097068 25961943 20686565) Epstein Barr virus nuclear antigen 1 IgG levels or multiple sclerosis ( 26819262) LDL cholesterol ( 30275531 25961943) Monocyte count ( 27863252) Monocyte percentage of white cells ( 27863252) Multiple sclerosis ( 31604244 24076602 19525955 21833088 27386562) Systemic lupus erythematosus ( 28714469) Total cholesterol levels ( 28334899 30275531)	Blood trace element (Se levels) ( 23720494) Periodontitis (Mean PAL) ( 24024966)
Interacting Genes		5 interacting genes: AURKB BIRC5 FBXO5 INCENP STX3	25 interacting genes: AURKA AURKB AURKC BIRC2 BIRC3 BIRC6 CASP3 CASP7 CASP9 CDCA8 CDK1 CDK4 DIABLO EVI5 FBXL7 H3-4 H3C14 HSP90AA1 INCENP KCNJ6 RAN RASA1 TLE3 XIAP XPO1
Entrez ID		7813	332
HPRD ID		04249	04520
Ensembl ID		ENSG00000067208	ENSG00000089685
Uniprot IDs		O60447 Q59FE7	A0A0B4J1S3 H3BLT4 O15392
PDB IDs			1E31 1F3H 1XOX 2QFA 2RAW 2RAX 3UEC 3UED 3UEE 3UEF 3UEG 3UEH 3UEI 3UIG 3UIH 3UII 3UIJ 3UIK 4A0I 4A0J 4A0N 6SHO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?