ZYX and HIPK3

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
HPRD (two hybrid)

		ZYX	HIPK3
Description		zyxin	homeodomain interacting protein kinase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Stress Fiber Nucleus Cytoplasm Cytosol Adherens Junction Focal Adhesion Phagocytic Vesicle	Nucleus Cytoplasm Cytosol Nuclear Body PML Body
	Molecular Function	RNA Binding Protein Binding Metal Ion Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell-cell Signaling Viral Process Stress Fiber Assembly Regulation Of Inflammatory Response Cellular Response To Interferon-gamma	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity
Pathways
Drugs		Artenimol
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717) Blood protein levels ( 28240269) White blood cell count (basophil) ( 27863252)	Anger ( 24489884) Obese vs. thin ( 30677029) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		30 interacting genes: ACTN1 ATXN1 BSPRY ENAH HIPK3 IMP3 LASP1 LATS1 LIN7A NEBL NEDD9 NME5 OPRM1 PDLIM5 PHF21A RABEPK RGS2 RPH3AL RTN4IP1 SIAH1 SREBF2 TES TUFT1 VASP VAV1 VAV3 WNK1 YPEL3 ZHX1 ZNF384	37 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I ZNF107 ZYX
Entrez ID		7791	10114
HPRD ID		03592	05111
Ensembl ID		ENSG00000159840	ENSG00000110422
Uniprot IDs		Q15942 Q96AF9	A8KAE4 Q9H422
PDB IDs
Enriched GO Terms of Interacting Partners?
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