USF1 and TAOK2

Number of citations of the paper that reports this interaction (PubMedID 30381292)
1

Data Source:
BioGRID (enzymatic study)

		USF1	TAOK2
Description		upstream transcription factor 1	TAO kinase 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex	Nucleoplasm Nucleolus Cytoplasm Cytosol Actin Cytoskeleton Integral Component Of Membrane Axon Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Neuron Projection Receptor Complex Dendritic Growth Cone Axonal Growth Cone
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Double-stranded DNA Binding Protein Binding Enzyme Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity ATP Binding Mitogen-activated Protein Kinase Kinase Binding Neuropilin Binding Tau Protein Binding Tau-protein Kinase Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Response To UV Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis	Activation Of MAPKK Activity Activation Of MAPK Activity Regulation Of Cell Growth Protein Targeting To Membrane Apoptotic Process Cellular Response To DNA Damage Stimulus Mitotic G2 DNA Damage Checkpoint Regulation Of Mitotic Cell Cycle Axonogenesis Regulation Of Cell Shape Cell Migration Signal Transduction By Protein Phosphorylation Actin Cytoskeleton Organization Stress-activated Protein Kinase Signaling Cascade G2 DNA Damage Checkpoint Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Positive Regulation Of Stress-activated MAPK Cascade Regulation Of Actin Cytoskeleton Organization Positive Regulation Of JNK Cascade Protein Autophosphorylation Focal Adhesion Assembly Stress-activated MAPK Cascade Basal Dendrite Morphogenesis Basal Dendrite Arborization
Pathways		Estrogen-dependent gene expression
Drugs			Dexfosfoserine
Diseases		Familial combined hyperlipidemia (FCHL)
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Metabolite levels (lipoprotein measures) ( 27005778) Night sleep phenotypes ( 27126917)	Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body mass index ( 29273807) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Metabolic syndrome ( 31589552) Schizophrenia ( 28991256 25056061 29483656 30285260)
Interacting Genes		16 interacting genes: APP ESR1 FBXO7 FOS FOSL1 GTF2I HDAC9 NFYA PLEKHF2 PPARGC1A PRKDC TAOK2 TCF3 TCFL5 TRAF2 USF2	12 interacting genes: BCKDK ELK1 KLHL12 MAP2K3 MAP2K6 MEGF10 RCHY1 TLE3 TUBA1A TUBA4A TUBB USF1
Entrez ID		7391	9344
HPRD ID		01880	18147
Ensembl ID		ENSG00000158773	ENSG00000149930
Uniprot IDs		A0A0S2Z4U5 P22415	Q9UL54
PDB IDs		1AN4
Enriched GO Terms of Interacting Partners?
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