UROD and HMGXB4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		UROD	HMGXB4
Description		uroporphyrinogen decarboxylase	HMG-box containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol	NURF Complex
	Molecular Function	Uroporphyrinogen Decarboxylase Activity Protein Binding	DNA Binding
	Biological Process	Protoporphyrinogen IX Biosynthetic Process Heme Biosynthetic Process	Endosome To Lysosome Transport Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway
Pathways		Heme biosynthesis
Drugs		Coproporphyrin I Coproporphyrinogen III
Diseases		Hepatic porphyria, including: Porphyria Cutanea Tarda (PCT); VHepatoerythropoietic porphyria; Acute Intermittent Porphyria (AIP); Variegate porphyria (VP); ALA-dehydratase deficiency porphyria (ALADP); Hereditary Coproporphyria (HCP)
GWAS			Hip circumference adjusted for BMI ( 25673412) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		7 interacting genes: CHD3 EGFR FAF1 FBXO7 HMGXB4 LRATD2 VIM	11 interacting genes: CREBBP EPM2A H3-4 HABP4 JMJD6 MX1 NR1H2 SRPK2 TNNT1 TSC22D1 UROD
Entrez ID		7389	10042
HPRD ID		01441	05267
Ensembl ID		ENSG00000126088	ENSG00000100281
Uniprot IDs		P06132	Q7Z641 Q9UGU5
PDB IDs		1JPH 1JPI 1JPK 1R3Q 1R3R 1R3S 1R3T 1R3V 1R3W 1R3Y 1URO 2Q6Z 2Q71 3GVQ 3GVR 3GVV 3GVW 3GW0 3GW3
Enriched GO Terms of Interacting Partners?
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