UBE2L3 and BRAF

  • Number of citations of the paper that reports this interaction (PubMedID 31015455)
  • 0
  • Data Source:
  • BioGRID (enzymatic study)

UBE2L3

BRAF

Description ubiquitin conjugating enzyme E2 L3 B-Raf proto-oncogene, serine/threonine kinase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Bipolar disorder ( 31043756)
  • Cerebrospinal fluid t-tau:AB1-42 ratio ( 26252872)
  • Cerebrospinal T-tau levels ( 26252872)
  • Mild influenza (H1N1) infection ( 26379185)
  • Response to Vitamin E supplementation ( 22437554)
  • Type 2 diabetes ( 28869590)
Interacting Genes 113 interacting genes: ANKIB1 AREL1 ARIH1 ARIH2 ATXN3 BRAF BRAP BRCA1 CBL CBLB CBLC CCNB1IP1 CDKN1B CUL9 DTX3 FBXO2 FOS HACE1 HECTD1 HECTD2 HECTD4 HECW1 HECW2 HERC1 HERC2 HERC3 HERC4 HERC6 HSPA4 HUWE1 IRF2BP1 ITCH KSR1 LIG4 LTN1 MAP2K1 MAPK6 MDM2 MEX3A MEX3C MID1 MKRN3 MUL1 MYCBP2 NEDD4 NEDD4L NFKBIA NR3C1 NRAS PIAS1 PIAS2 PJA1 POLR2A PRKN PTEN RAF1 RBCK1 RBX1 RC3H1 RELA RNF103 RNF113B RNF114 RNF125 RNF14 RNF144A RNF144B RNF150 RNF168 RNF170 RNF19A RNF19B RNF2 RNF20 RNF213 RNF216 RNF220 RNF31 RNF7 RTF2 SMAD4 SMAD7 SMURF1 SMURF2 SPOP STUB1 TP53 TRAF6 TRAF7 TRIM21 TRIM23 TRIM25 TRIM28 TRIM31 TRIM39 TRIM55 TRIP12 UBA1 UBA5 UBA6 UBA7 UBASH3A UBC UBE3A UBE3C UBOX5 UBR4 UBR5 VPS11 WIPI2 WWP1 WWP2 YWHAQ 39 interacting genes: AKT1 ARAF AURKA BAD CCDC88A HRAS ITCH KRAS LATS2 MAP2K1 MAP2K2 MAP2K3 MAP2K6 MAPK1 MRAS NANOG OIP5 PAK2 PPP2CA PPP2R2A PRKACA PRKCE RAF1 RAP1A RAP1GAP RASSF1 RHEB SFN SGK1 SPRY2 STK11 TERF1 TERT UBE2L3 YWHAB YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 7332 673
HPRD ID 04762 01264
Ensembl ID ENSG00000185651 ENSG00000157764
Uniprot IDs A0A024R1A4 P68036 A0A2R8Y8E0 P15056
PDB IDs 1C4Z 1FBV 3SQV 3SY2 4Q5E 4Q5H 5HPT 5TTE 5UDH 6CP2 6DJW 6DJX 6N13 1UWH 1UWJ 2FB8 2L05 3C4C 3D4Q 3IDP 3II5 3NY5 3OG7 3PPJ 3PPK 3PRF 3PRI 3PSB 3PSD 3Q4C 3Q96 3SKC 3TV4 3TV6 4CQE 4DBN 4E26 4E4X 4EHE 4EHG 4FC0 4FK3 4G9C 4G9R 4H58 4JVG 4KSP 4KSQ 4MBJ 4MNE 4MNF 4PP7 4R5Y 4RZV 4RZW 4WO5 4XV1 4XV2 4XV3 4XV9 4YHT 5C9C 5CSW 5CSX 5CT7 5FD2 5HI2 5HID 5HIE 5ITA 5J17 5J18 5J2R 5JRQ 5JSM 5JT2 5VAL 5VAM 5VR3 5VYK 6B8U 6CAD 6N0P 6N0Q 6NSQ 6NYB 6PP9 6Q0J 6Q0K 6Q0T 6U2G 6U2H 6UAN
Enriched GO Terms of Interacting Partners?
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