UBE2A and RNF4

Number of citations of the paper that reports this interaction (PubMedID 27678051)
3

Data Source:
BioGRID (pull down)

		UBE2A	RNF4
Description		ubiquitin conjugating enzyme E2 A	ring finger protein 4
Image
GO Annotations	Cellular Component	Chromatin Nuclear Chromatin XY Body Nucleoplasm Cytosol HULC Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Body PML Body Microtubule End
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Ubiquitin Conjugating Enzyme Activity	DNA Binding Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Nucleosome Binding SUMO Polymer Binding Identical Protein Binding Androgen Receptor Binding
	Biological Process	Protein Polyubiquitination Blastocyst Hatching DNA Repair Postreplication Repair Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cell Proliferation Response To UV Protein Ubiquitination Histone Ubiquitination Histone H2A Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Maternal Process Involved In Female Pregnancy Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination	Androgen Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Arsenic-containing Substance Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Regulation Of Spindle Assembly Regulation Of Kinetochore Assembly
Pathways		Synthesis of active ubiquitin: roles of E1 and E2 enzymes E3 ubiquitin ligases ubiquitinate target proteins Antigen processing: Ubiquitination & Proteasome degradation	Processing of DNA double-strand break ends Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Brain connectivity ( 23471985)	Colorectal adenoma (advanced) ( 29228715) Colorectal cancer ( 29228715) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Dimensional psychopathology (Social) ( 29496196) Tourette syndrome ( 30818990)
Interacting Genes		26 interacting genes: CBX5 CDK1 CDK2 CDK9 CDKN2A CRMP1 EEF1D H2BC21 HLTF KCMF1 MDM2 PCNA PRKN RAD18 RC3H1 RNF20 RNF4 RNF40 SDCBP TP53 TRIM27 UBA1 UBR1 UBR3 UBR5 ZMYM2	39 interacting genes: AR ATXN1 ESR1 GSC2 H3C14 HMGA1 HNF4A IKBKG PATZ1 PGR SKIL SP1 SRPK2 SUMO1 SUMO2 TBP TCF20 TERF2 TRAIP TRIM28 TRPS1 UBC UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L6 UBE2N UBE2T UBE2W UEVLD
Entrez ID		7319	6047
HPRD ID		02422	04167
Ensembl ID		ENSG00000077721	ENSG00000063978
Uniprot IDs		A0A0D9SG71 P49459	P78317
PDB IDs		6CYO 6CYR	2EA6 2XEU 4PPE
Enriched GO Terms of Interacting Partners?
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